Table 1 Baseline characteristics of patients

Variables at baseline assessment

Gender

144

0.30^Chi2

 Female

22 (22.0%)

14 (31.8%)

 Male

78 (78.0%)

30 (68.2%)

Age in years mean (\(\pm\)SD)

144

59.4 (\(\pm\)14.3)

56.6 (\(\pm\)14.6)

0.28^TT

BMI median (IQR)

142

29.2 (26.3–33.9)

28.4 (24.4–33.6)

0.26 ^MW

Diabetes yes n (%)

141

33 (34%)

8 (18.2%)

0.086^Chi2

Pulmonary diseases yes n (%)

144

22 (22%)

9 (20.4%)

0.99^Chi2

Hypertension yes n (%)

137

54 (55.1%)

16 (41.0%)

0.19^Chi2

Chronic kidney disease yes n (%)

144

4 (4%)

5 (11.4%)

0.19^F

Min PaO₂/FiO₂ mean (\(\pm\)SD)

144

152.5 (\(\pm\)74.6)

146.6 (\(\pm\)59.1)

0.65^TT

Max PaO₂/FiO₂ mean (\(\pm\)SD)

144

234.1 (\(\pm\)96.4)

264.6 (\(\pm\)95.6)

0.08^TT

SOFA baseline mean (\(\pm\)SD)

129

10.8 (\(\pm\)2.9)

11.1 (\(\pm\)4.2)

0.68^TT

SOFA after 5 days mean (\(\pm\)SD)

122

8.8 (\(\pm\)4.0)

9.3 (\(\pm 5\).0)

0.53^TT

Max FiO₂/day

Max P max mean (\(\pm\)SD)

140

28.4 (\(\pm\)4.5)

27.3 (\(\pm\)8.0)

0.29^TT

Max P mean mean (\(\pm\)SD)

132

20.5 (\(\pm\)4.0)

20.0 (\(\pm\)6.4)

0.61^TT

Max compliance mean (\(\pm\)SD)

109

58.1 (\(\pm\)25.1)

56.9 (\(\pm\)18.9)

0.83^TT

Driving pressure mean (\(\pm\)SD)

124

12.4 (\(\pm\)4.2)

13.3 (\(\pm\)4.4)

0.29 ^T

Variables during the follow-up

ECMO yes n (%)

144

32 (32%)

6 (13.6%)

0.036^Chi2

Duration of ECMO median (IQR)

38

18 (9.5–41)

13 (9.5–20.7)

0.42 ^MW

Acute Kidney Insufficiency n (%)

144

24 (24%)

15 (34.1%)

0.293^Chi2

CRRT yes n (%)

144

20 (20%)

15 (34.1%)

0.109^Chi2

Positive blood culture* n (%)

143

31 (31%)

10 (23.3%)

0.46^Chi2

Pneumonia n (%)

143

91 (91%)

30 (69.8%)

0.003^Chi2

Bacterial infection n (%)

143

78 (78%)

30 (69.8%)

0.40^Chi2

Viral infection n (%)

143

83 (83%)

18 (41.9%)

< 0.001^Chi2

Fungal infection n (%)

143

48 (48%)

15 (34.9%)

0.21^Chi2

Therapy

144

0.86^Chi2

 NaCl n (%)

51 (51%)

21 (47.7%)

 Ilosprost n (%)

49 (49%)

23 (52.3%)

Time ICU days

143

13 (8–21)

16 (11–34)

0.040 ^MW