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Table 1 General baseline data, overall and by period, of the HIV cohort from OutcomeReaâ„¢

From: Outcomes in critically Ill HIV-infected patients between 1997 and 2020: analysis of the OUTCOMEREA multicenter cohort

 

Global

(n = 630)

1997–2006

(n = 215)

2007–2015

(n = 336)

2016–2020

(n = 79)

p value

Age (year)

46.7 [38; 55]

41.8 [36; 51]

48.1 [39; 55]

54.3 [44; 58]

 < 0.001

Body mass index

21.8 [19; 25]

20.8 [19; 23]

22.7 [20; 25]

23 [20; 27]

 < 0.001

Katz independence scale

6 [6; 6]

NA

6 [6; 6]

6 [6; 6]

0.991

Sex (male)

440 (69.8%)

143 (66.5%)

242 (72%)

55 (69.6%)

0.350

Diabetes

48 (7.6%)

3 (1.4%)

35 (10.4%)

10 (12.7%)

 < 0.001

Obesity

34 (5.9%)

4 (2.5%)

18 (5.4%)

12 (15.2%)

 < 0.001

Substance abuse

79 (13.7%)

30 (18.6%)

40 (12%)

9 (11.4%)

0.464

Precariousness (n = 55, 206, 59)

221 (69.1%)

40 (72.7%)

142 (68.9%)

40 (66.1%)

0.446

Hepatitis

 B

25 (4%)

6 (2.8%)

18 (5.4%)

1 (1.3%)

0.901

 C

66 (10.5%)

13 (6%)

46 (13.7%)

7 (8.9%)

0.098

Chronic disease (KNAUS)

 Hepatic

47 (7.5%)

11 (5.1%)

30 (8.9%)

6 (7.6%)

0.229

 Cardiovascular

45 (7.1%)

8 (3.7%)

31 (9.2%)

6 (7.6%)

0.066

 Renal

41 (6.5%)

7 (3.3%)

27 (8%)

7 (8.9%)

0.027

 Respiratory

43 (6.8%)

4 (1.9%)

31 (9.2%)

8 (10.1%)

0.001

Solid neoplasia

23 (3.6%)

1 (0.5%)

15 (4.5%)

7 (8.9%)

 < 0.001

Non-AIDS hemopathy

8 (1.5%)

1 (0.7%)

5 (1.6%)

2 (2.7%)

0.134

Pre-admission immunosuppression (excluding HIV/AIDS)

 Aplasia

28 (4.4%)

11 (5.1%)

14 (4.2%)

3 (3.8%)

0.560

 Corticoid

21 (3.3%)

5 (2.3%)

12 (3.6%)

4 (5.1%)

0.226

 Anticancer chemotherapy

91 (14.4%)

26 (12.1%)

56 (16.7%)

9 (11.4%)

0.644

 SOT

6 (0.9%)

0

4 (1.2%)

2 (2.5%)

0.037

 Other

16 (2.5%)

0

10 (3%)

6 (7.6%)

 < 0.001

Pre-ICU hospitalization stay (day)

1 [1; 3]

1 [1; 5]

1 [1; 3]

1 [1; 2]

0.324

Medical reason for ICU admission

591 (94%)

199 (92.6%)

318 (94.6%)

74 (94.9%)

0.309

SOFA upon ICU admission

5 [2; 8]

5 [3; 8]

5 [2; 8]

6 [1; 9]

0.668

Main purpose for ICU admission*

    

0.626

 Multivisceral failure

12 (1.9%)

6 (2.8%)

3 (0.9%)

3 (3.8%)

 

 Septic shock

77 (12.3%)

19 (8.9%)

48 (14.4%)

10 (12.8%)

 Hemorrhagic shock

14 (2.2%)

6 (2.8%)

6 (1.8%)

2 (2.6%)

 Cardiogenic shock

8 (1.3%)

4 (1.9%)

2 (0.6%)

2 (2.6%)

 Shock (other)

18 (2.9%)

6 (2.8%)

10 (3%)

2 (2.6%)

 Acute respiratory distress

223 (35.6%)

85 (39.7%)

106 (31.7%)

32 (41%)

 COPD decompensation

4 (0.6%)

0

4 (1.2%)

0

 Acute renal failure

53 (8.5%)

14 (6.5%)

34 (10.2%)

5 (6.4%)

 Coma

109 (17.4%)

40 (18.7%)

57 (17.1%)

12 (15.4%)

 Continuous monitoring

103 (16.4%)

33 (15.4%)

60 (18%)

10 (12.8%)

 Scheduled surgery

5 (0.8%)

1 (0.5%)

4 (1.2%)

0

Syndromic diagnosis on admission*

 Infection

342 (54.3%)

131 (60.9%)

166 (49.5%)

45 (57%)

0.133

  Bacteremia

29 (4.6%)

15 (7%)

9 (2.7%)

5 (6.3%)

  Pneumonia

179 (28.4%)

80 (37.2%)

74 (22%)

25 (31.6%)

  Meningitis

52 (8.2%)

27 (12.6%)

16 (4.8%)

9 (11.4%)

 Cardiovascular

40 (6.3%)

14 (6.5%)

22 (6.5%)

4 (5.1%)

0.882

  Cardiorespiratory arrest

19 (3%)

6 (2.8%)

9 (2.7%)

4 (5.1%)

  Acute lung edema

13 (2.1%)

4 (1.9%)

9 (2.7%)

0

  Myocardial infarction

3 (0.5%)

3 (1.4%)

0

0

  Stroke

5 (0.8%)

1 (0.5%)

4 (1.2%)

0

  1. Bold indicates the significance of the result (p < 0.05)
  2. AIDS acquired immunodeficiency syndrome, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, SOFA sepsis-related organ failure assessment, SOT solid organ transplant
  3. *Only one proposition for each patient