Table 1 Summary of norepinephrine equivalent formulas

Patel et al. [22]

2002

Anesthesiology

Norepinephrine dose (µg/min) + epinephrine dose (µg/min) + 1/4 × dopamine dose (µg/kg/min)

Russell et al. [13] (VASST)

2008

New England Journal of Medicine

Norepinephrine dose (µg/min) + 1/2 × dopamine dose (µg/kg/min) + epinephrine dose (µg/min) + 1/10 × phenylephrine dose (µg/min)

Brown et al. [12]

2013

Chest

Norepinephrine dose (µg/kg/min) + epinephrine dose (µg/kg/min) + 1/100 × dopamine dose (µg/kg/min) + 5 × vasopressin dose (U/min) + 0.45 × phenylephrine dose (µg/kg/min)

Ralib et al. [23]

2013

Clinical Nephrology

Norepinephrine dose (μg/min) + 500 × vasopressin dose (U/min) + epinephrine dose (μg/min) + 1/3 × phenylephrine dose (μg/min) + 1/100 × dopamine dose (μg/min)

Gutsche et al. [21]

2017

Anesthesia & Analgesia

Norepinephrine dose (μg/min) + 1/2 × dopamine dose (μg/kg/min) + epinephrine dose (μg/min) + 1/10 × phenylephrine dose (μg/min) + 200 × vasopressin dose (U/min)

Khanna et al. [15] (ATHOS-3)

2017

New England Journal of Medicine

Norepinephrine dose (µg/kg/min) + epinephrine dose (µg/kg/min) + 1/150 × dopamine dose (µg/kg/min) + 1/10 × phenylephrine dose (µg/kg/min) + 2.5 × vasopressin dose (U/min)

Laterre et al. [16] (SEPSIS-ACT)

2019

JAMA

Norepinephrine dose (µg/min) + epinephrine dose (µg/min) + 1/100 × dopamine dose (µg/min) + 1/2.2 × phenylephrine dose (µg/kg/min)

Goradia et al. [20]

2021

Journal of Critical Care

Norepinephrine dose (µg/kg/min) + epinephrine dose (µg/kg/min) + 1/10 × phenylephrine dose (µg/kg/min) + 1/100 × dopamine dose (µg/kg/min) + 1/8 × metaraminol (µg/kg/min) + 2.5 × vasopressin dose (U/min) + 10 × angiotensin II dose (µg/kg/min)

Our manuscript

2022

Norepinephrine dose (µg/kg/min) + epinephrine dose (µg/kg/min) + 1/100 × dopamine dose (µg/kg/min) + 0.06 × phenylephrine dose (µg/kg/min) + 2.5 × vasopressin dose (U/min) + 0.0025 × angiotensin II dose (ng/kg/min) + 10 × terlipressin dose (µg/kg/min) + 0.2 × methylene blue dose (mg/kg/h) + 8 × metaraminol dose (µg/kg/min) + 0.02 × hydroxocobalamin dose (g) + 0.4 × midodrine dose (µg/kg/min)