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Table 3 Adverse event of TTM among the study population according to targeted temperature

From: The impact of different targeted temperatures on out-of-hospital cardiac arrest outcomes in patients receiving extracorporeal membrane oxygenation: a nationwide cohort study

 

All patients

Original cohort

Crude analysis

OR (95% CI)

Multivariable analysis

AOR (95% CI)a

n-TTM

h-TTM

N = 617

N = 151

N = 466

Any adverse event of TTM

124 (20.1)

29 (19.2)

95 (20.4)

1.08 (0.68–1.78)

1.08 (0.63–1.82)

Bleeding

70 (11.4)

12 (7.9)

58 (12.4)

1.65 (0.86–3.16)

1.47 (0.69–3.10)

Arrhythmia

31 (5.2)

7 (4.6)

24 (5.2)

1.12 (0.47–2.65)

1.28 (0.50–3.31)

Hypotension

76 (12.3)

20 (13.2)

56 (12.0)

0.90 (0.52–1.55)

1.04 (0.55–1.95)

Infection

24 (3.9)

2 (1.3)

22 (4.7)

3.69 (0.86–15.9)

6.09 (0.79–46.8)

Other

8 (1.3)

5 (3.3)

3 (0.6)

0.19 (0.04–0.80)

0.08 (0.01–0.67)

  1. Shown data are calculated for patients for whom data were available (n = 617/890)
  2. Values are expressed numbers (percentages) unless indicated otherwise
  3. TTM targeted temperature management, n-TTM normothermic TTM, h-TTM hypothermic TTM, OR odds ratio, AOR adjusted odds ratio, CI confidence interval
  4. aShown is the AOR from the multivariable logistic regression analysis adjusted for age, sex, cause of arrest, bystander witness, bystander CPR, use of public-access AEDs, prehospital epinephrine administration, prehospital advanced airway management, time from EMS call to contact with the patients, time from EMS contact with the patients to hospital arrival, type of centre, the annual volume of ECMO used for OHCA at each centre, success of PCI, timing of ECMO start, time from hospital arrival to induction of ECMO, and TTM induction time