Table 1 Baseline characteristics of patients who received norepinephrine and those who did not receive norepinephrine during their stay
From: Mobilisation of critically ill patients receiving norepinephrine: a retrospective cohort study
No norepinephrine | Norepinephrine | p value | |
|---|---|---|---|
n | 8245 | 4217 | |
Age | 66.0 [54.0, 77.0] | 67.0 [56.0, 77.0] | 0.213 |
Elixhauser comorbidity index [19] | 0.0 [0.0, 11.0] | 4.0 [0.0, 15.0] | < 0.001 |
Admission APACHE II | 20.0 [13.0, 23.0] | 20.0 [18.0, 28.0] | < 0.001 |
Admission SOFA | 4.0 [2.0, 7.0] | 6.0 [3.0, 9.0] | < 0.001 |
Median absolute RASS | 0.5 [0.0, 1.0] | 1.0 [0.0, 2.0] | < 0.001 |
Female sex | 3380 (41.0) | 1693 (40.1) | 0.37 |
Obesity (ICD-10) | 190 (2.3) | 132 (3.1) | 0.007 |
Dialysis | 958 (11.6) | 760 (18.0) | < 0.001 |
ECMO | 113 (1.4) | 122 (2.9) | < 0.001 |
Highflow | 1830 (22.2) | 1079 (25.6) | < 0.001 |
Intubated | 1504 (18.2) | 1390 (33.0) | < 0.001 |
NIV | 2710 (32.9) | 1822 (43.2) | < 0.001 |
Tracheostomy (%) | 316 (3.8) | 345 (8.2) | < 0.001 |
Type of ICU (%) | < 0.001 | ||
Cardiac surgery | 134 (1.6) | 814 (19.3) | |
Interdisciplinary operative | 4096 (49.7) | 2124 (50.4) | |
Internal medicine | 2882 (35.0) | 413 (9.8) | |
Multiple specialties | 419 (5.1) | 460 (10.9) | |
Neurocritical | 714 (8.7) | 406 (9.6) | |
COVID-19 (%) | 496 (6.0) | 293 (6.9) | 0.047 |