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Fig. 2 | Critical Care

Fig. 2

From: Gene signature for the prediction of the trajectories of sepsis-induced acute kidney injury

Fig. 2

Sepsis-induced acute kidney injury trajectories. A Flowchart showing the transition of the severity of AKI as measured by renal component of the SOFA score. B Comparisons of serum lactate, creatinine and urine output between the four subtypes of sepsis-induced AKI. The boxplots describe the distribution of these variables. The error bar indicates the 95% confidence interval. The short line in the box indicates the median value. The four subtypes are denoted by filling colors. C Line plot showing the differences in clinical variables between the four subtypes. Statistical significance was annotated as: ns for > 0.05; * < 0.05; ** < 0.01, *** < 0.001, **** < 0.0001. AKI = acute kidney injury; scvo = central venous oxygen saturation; pcvo = central venous oxygen pressure; abe = actual base excess; pcvco = central venous carbon dioxide pressure; gcs = Glasgow coma scale; plt = platelet; sapmin = minimum systolic arterial pressure; cl = chloride; pao = arterial partial pressure of oxygen; pha = arterial pH; paco = arterial partial pressure of carbon dioxide; mapmin = minimum mean arterial pressure; phcv = central venous pH; rrmax = maximum respiratory rate; tmin = minimum temperature; hct = hematocrit; sapmax = maximum systolic arterial pressure; tt = thrombin time; ca = ionized calcium; fio = fraction of inspired oxygen; rrmin = minimum respiratory rate; inr = international normalized ratio; lac = lactate; SOFA = sequential organ failure assessment; alb = albumin

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