Table 1 Characteristics of healthy individuals and patients with severe sepsis
Characteristic | Healthy Ind | Sepsis Placebo | Sepsis Steroid |
|---|---|---|---|
Male, No. (%)/total No | 10/20 (50) | 53/90 (59) | 60/90 (67) |
Age, mean (SD), y | 33.1 (9.9)* | 62.9 (15.7) | 64.3 (14.7) |
Focus of primary infection, No./total No. (%) | |||
 Known focus | n.a | 76/90 (84) | 83/90 (92) |
 Pneumonia | n.a | 36/90 (40) | 28/90 (31) |
 Intraabdominal infection | n.a | 2/90 (2.2) | 6/90 (6.7) |
 Urogenital | n.a | 12/90 (13) | 14/90 (16) |
 Other infection | n.a | 26/90 (29) | 35/90 (39) |
Organ dysfunction, No./total No. (%) | |||
 Central nervous system | n.a | 21/90 (23) | 17/90 (19) |
 Respiratory | n.a | 59/90 (66) | 59/90 (66) |
 Renal | n.a | 41/90 (46) | 41/90 (46) |
 Microcirculatory | n.a | 14/90 (16) | 24/90 (27) |
 Coagulation | n.a | 15/90 (16) | 22/90 (24) |
 SOFA score, mean (SD) | n.a | 6.0 (2.3) | 6.4 (2.5) |
 SAPS II score, mean (SD) | n.a | 50.9 (9.7) | 52.7 (14.7) |
Outcome | |||
 Septic Shock, No./total No. (%) | n.a | 18/90 (20) | 18/90 (20) |
 Mortality, No./total No. (%) in-hospital | n.a | 12/90 (13) | 10/89 (11) |
 Mortality, No./total No. (%) 28 day | n.a | 8/88 (9.1) | 8/90 (8.9) |
 Mortality, No./total No. (%) 90 day | n.a | 15/86 (17) | 17/89 (19) |