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Table 3 Effects of PEEP level on respiratory and circulatory function in patients with acute respiratory distress syndrome and chronic obstructive pulmonary disease according to the titration method used

From: Electrical impedance tomography for titration of positive end-expiratory pressure in acute respiratory distress syndrome patients with chronic obstructive pulmonary disease

Respiratory mechanics and hemodynamic parameters

EIT

ARDSnet protocol

T

P-value

Ppeak (cm H2O)

29.5 ± 4.10

33.64 ± 5.19

6.340

<0.001

Pplat (cm H2O)

16.5 ± 4.35

20.93 ± 5.37

4.030

0.001

PD (cm H2O)

10.0 ± 3.51

10.57 ± 4.6

0.597

0.562

Cst (mL/cm H2O)

42.61 ± 13.77

38.39 ± 13.86

2.186

0.049

Vd/Vt (%)

48.29 ± 6.78

55.14 ± 8.85

4.686

<0.001

VR

1.63 ± 0.33

1.87 ± 0.33

7.373

<0.001

MP (J/min)

13.92 ± 2.18

15.87 ± 2.53

5.15

<0.001

EELV (mL)

1326 ± 201.5

1440 ± 182.6

2.791

0.019

Qs/Qt (%)

17.8 ± 7.16

16.5 ± 4.46

0.966

0.352

pH

7.39 ± 0.06

7.39 ± 0.07

0.219

0.836

PaCO2 (mmHg)

54.07 ± 6.78

63.21 ± 8.26

7.054

<0.001

P/F (mmHg)

220.6 ± 67.73

237.2 ± 73.01

1.749

0.105

CI (L/min/m2)

3.41 ± 0.50

3.02 ± 0.43

4.774

<0.001

CVP (cm H2O)

12.12 ± 4.69

13.43 ± 3.88

1.745

0.105

MAP (mmHg)

78.5 ± 7.3

82.1 ± 12.4

1.220

0.244

HR (bpm)

81.7 ± 15.8

80.8 ± 14.7

0.618

0.547

NE (µg/kg/min)

0.105 ± 0.077

0.119 ± 0.076

2.590

0.022

DO2 (mL/min/m2)

466.4 ± 71.08

411.1 ± 69.71

3.997

0.001

ScvO2 (%)

71.08 ± 9.29

69.7 ± 8.09

1.029

0.322

  1. The data are presented as the mean ± standard deviation
  2. ARDS acute respiratory distress syndrome, CI cardiac index, COPD chronic obstructive pulmonary disease, Cst static compliance, CVP central venous pressure, DO2 oxygen delivery, EELV end-expiratory lung volume, EIT electrical impedance tomography, HR heart rate, MAP mean arterial pressure, MP mechanical power, NE norepinephrine, PaCO2 partial pressure of carbon dioxide in arterial blood, PD driving pressure, PEEP positive end-expiratory pressure, P/F, PaO2/FiO2 ratio ppeak, peak airway pressure, Pplat plateau airway pressure, Qs/Qt pulmonary shunt fraction, Vd/Vt dead space ventilation ratio, ScvO2 central venous oxygen saturation, VR ventilation ratio