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Table 1 Baseline and resuscitation characteristics

From: Extracorporeal versus conventional cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: a secondary analysis of the Prague OHCA trial

Parameter

Prehospital ROSC (n = 83)

No ROSC and ACLS (n = 81)

No ROSC and ECPR (n = 92)

P value

Age (years)

55 (49–63.8)

58 (48–66)

58.5 (45–65)

0.69

Sex

 Woman

14 (16.9%)

14 (17.3%)

16 (17.4%)

1.0

 Man

69 (83.1%)

67 (82.7%)

76 (82.6%)

Medical history

 Hypertension

38 (48.1%)

13 (43.3%)

38 (46.3%)

0.9

 Coronary artery disease

14 (17.9%)

5 (17.2%)

15 (18.8%)

0.98

 Chronic heart failure

4 (5.1%)

3 (11.5%)

9 (11.1%)

0.35

 Diabetes

14 (17.9%)

9 (31%)

13 (16.3%)

0.21

 Chronic kidney disease

3 (3.8%)

0 (0%)

2 (2.5%)

0.58

 COPD

7 (9.0%)

1 (3.8%)

2 (2.5%)

0.19

 ICD implanted

0 (0.0%)

1 (2.7%)

2 (2.2%)

0.37

Location of cardiac arrest

 Home

26 (31.3%)

24 (29.6%)

26 (28.3%)

0.15

 Public place

38 (45.8%)

29 (35.8%)

31 (33.7%)

 EMS

4 (4.8%)

12 (14.8%)

20 (21.7%)

 Health facility

0 (0%)

1 (1.2%)

1 (1.1%)

 Car

2 (3.6%)

5 (6.2%)

7 (7.6%)

 Hotel

4 (4.8%)

5 (6.2%)

1 (1.1%)

 Workplace

8 (9.6%)

5 (6.2%)

6 (6.5%)

Initial rhythm

 VF

63 (75.9%)

36 (44.4%)

57 (62%)

 < 0.001

 Asystole

14 (16.9%)

23 (28.4%)

18 (19.6%)

 PEA

6 (7.2%)

22 (27.2%)

17 (18.5%)

Time of CPR (time to death/ROSC or ECPR) (min)

31 (24–39.8)

66 (46–82.3)

60 (51–70)

< 0.001

Bystander CPR

81 (97.6%)

80 (98.8%)

91 (98.9%)

0.75

Time from collapse to EMS arrival (min)

9 (7–11)

9 (6–12)

8 (6–10)

0.6

Time from collapse to ACLS (physician arrival) (min)

11 (8.3–14)

11 (8–14.3)

10 (6–13)

0.06

Time from collapse to randomization (min)

24 (19–29.8)

26 (21–34.3)

24.5 (19.5–30)

0.27

Time to ECLS (min)

NA

NA

61 (55–70)

NA

Time of implantation (door to ECLS) (min)

NA

NA

12 (11–14)

NA

Number of epinephrine doses prehospitally (mg)

3 (2–4.8)

6 (5–9)

4 (2–6)

< 0.001

Dose of amiodarone prehospitally (mg) *

300 (0–300)

225 (0–300)

300 (0–300)

0.6

Number of defibrillations prehospitally

3 (2–5)

1 (0–4)

3 (0–6)

0.02

  1. Highlighted in bold are the values which are statistically significant (less than 0.05)
  2. *For patients with initial VF
  3. ACLS advanced cardiac life support, CPR cardiopulmonary resuscitation, COPD chronic obstructive pulmonary disease, ECPR extracorporeal cardiopulmonary resuscitation, ECLS extracorporeal life support, EMS emergency medical service, ICD implantable cardioverter defibrillator, PEA pulseless electrical activity, ROSC return of spontaneous circulation, VF ventricular fibrillation