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Fig. 4 | Critical Care

Fig. 4

From: An area under the concentration–time curve threshold as a predictor of efficacy and nephrotoxicity for individualizing polymyxin B dosing in patients with carbapenem-resistant gram-negative bacteria

Fig. 4

Classification and regression tree results for the incidence of AKI and clinical efficacy. AUCss,24 h for AKI (a) and clinical efficacy (b); C0h for AKI (c) and clinical efficacy (d). AKI, acute kidney injury; AUCss,24 h, the area under the plasma concentration–time curve across 24 h at steady state; and C0h, trough concentration

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Critical Care

ISSN: 1364-8535