Table 1 Baseline patients’ characteristics, comorbidities, pre-hospital settings/interventions of the overall population and stratified according to oxygen values
Overall (n = 1418, 100.0%) | PaO2 < 60 mmHg (n = 79, 5.6%) | PaO2 60–300 mmHg (n = 1239, 87.4%) | PaO2 > 300 mmHg (n = 100, 7.1%) | p value | |
|---|---|---|---|---|---|
Baseline patient characteristics | |||||
Age, years, median (IQR) | 65 (55; 74) | 66 (57; 75) | 65 (55; 74) | 66 (56; 74) | 0.415 |
Gender, female, n (%) | 292 (20.6) | 13 (16.5) | 250 (20.2) | 29 (29.0) | 0.071 |
Height, cm, median (IQR) | 175 (170; 180) | 176 (170; 180) | 175 (170; 180) | 170 (165; 179) | 0.005 |
Weight, kg, median (IQR) | 80 (73; 90) | 85 (80; 93) | 80 (73; 91) | 80 (70; 88) | 0.001 |
BMI, kg/m2, median (IQR) | 26.3 (24.1; 29.7) | 27.4 (25.0; 30.6) | 26.3 (24.1; 29.7) | 26.1 (23.3; 28.4) | 0.021 |
Chronic comorbidities | |||||
Hypertension, yes, n (%) | 504 (35.5) | 25 (31.6) | 449 (36.2) | 30 (30.0) | 0.115 |
Diabetes mellitus, yes, n (%) | 266 (18.8) | 15 (19.0) | 234 (18.9) | 17 (17.0) | 0.896 |
Myocardial infarction, yes, n (%) | 230 (16.2) | 14 (17.7) | 201 (16.2) | 15 (15.0) | 0.244 |
Percutaneous coronary intervention, yes, n (%) | 210 (14.8) | 14 (17.7) | 181 (14.6) | 15 (15.0) | 0.130 |
Coronary artery bypass graft, yes, n (%) | 112 (7.9) | 7 (8.9) | 98 (7.9) | 7 (7.0) | 0.219 |
Heart failure, yes, n (%) | 145 (10.2) | 9 (11.4) | 127 (10.3) | 9 (9.0) | 0.206 |
Charlson comorbidity index, points, median (IQR) | 4.0 (2.0; 5.0) | 4.0 (3.0; 6.0) | 4.0 (2.0; 5.0) | 4.0 (2.3; 5.8) | 0.517 |
Pre-hospital setting/interventions | |||||
Location of cardiac arrest, n (%) | |||||
Home | 741 (52.3) | 42 (53.2) | 638 (51.5) | 61 (61.0) | |
Public place | 509 (35.9) | 27 (34.2) | 452 (36.5) | 30 (30.0) | |
Other | 168 (11.8) | 10 (12.7) | 149 (12.0) | 9 (9.0) | 0.474 |
Witnessed cardiac arrest, yes, n (%) | 1295 (91.3) | 71 (89.9) | 1131 (91.3) | 93 (93.0) | 0.753 |
Bystander performed CPR, yes, n (%) | 1148 (81.0) | 63 (79.7) | 1007 (81.3) | 78 (78.0) | 0.696 |
Type of rhythm, n (%) | |||||
Not shockable | 390 (27.5) | 24 (30.4) | 331 (26.7) | 35 (35.0) | |
Shockable | 1028 (72.5) | 55 (69.6) | 908 (73.3) | 65 (65.0) | 0.558 |
Time of ROSC, minutes, median (IQR) | 25 (17; 39) | 25 (19; 39) | 25 (17; 39) | 25(18.3; 35.8) | 0.558 |
TTM randomization treatment, n (%) | |||||
Normothermia | 712 (50.2) | 46 (58.2) | 615 (49.6) | 51 (51.0) | 0.330 |
Hypothermia | 706 (49.8) | 33 (41.8) | 624 (50.4) | 49 (49.0) |