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Fig. 2 | Critical Care

Fig. 2

From: Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

Fig. 2

Adjusted hourly trajectories of partial pressure of oxygen according to 6-month survival status. Left panel shows the predicted partial pressure of oxygen (PaO2) trajectories according to survival status. Right panel shows the PaO2 differences between survivors and non-survivors at each time point. For this analysis, mixed regression model included a random intercept on patients ID and a random coefficient on the time variable (time elapsed between measurements). These predicted trajectories were adjusted for TTM2 randomization arms, age (year), gender, Charlson comorbidity index, state of shock at admission, return to spontaneous circulation-ROSC- time, initial cardiac rhythm (shockable vs non-shockable), witnesses of cardiac arrest, respiratory rate (breath/min), plateau pressure (cmH2O),positive end expiratory pressure (cmH2O), arterial partial pressure of carbon dioxide, PaCO2 (mmHg), pH, Base excess (mEq/L), and fraction of inspired O2 (%). Right panel confirmed that the differences between these two trajectories (survivors/non-survivors) are statistically significant up to the first 32 h of measurement (omnibus p value = 0.0074). ICU, Intensive Care Unit

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Critical Care

ISSN: 1364-8535