Table 1 Characteristics of patients discharged alive in the FROG-ICU cohort
From: Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors
Variables | n | Global median (Q1–Q3) or n (%) | n | No in-ICU transfusion median (Q1–Q3) or n (%) | n | In-ICU Transfusion median (Q1–Q3) or n (%) | p value |
|---|---|---|---|---|---|---|---|
Demographic | |||||||
Age (years) | 1551 | 61 (49–73) | 892 | 60 (48–71) | 659 | 63 (51–74) | 0.0003 |
Female gender | 1551 | 566 (36%) | 892 | 314 (35%) | 659 | 252 (38%) | 0.22 |
Medical history | |||||||
Charlson score | 1551 | 1 (0–2) | 892 | 0 (0–2) | 659 | 1 (0–2) | < 0.0001 |
Hypertension | 1550 | 634 (41%) | 892 | 337 (38%) | 658 | 297 (45%) | 0.004 |
Coronary artery disease | 1550 | 123 (8%) | 892 | 49 (5%) | 658 | 74 (11%) | < 0.0001 |
Chronic heart failure | 1550 | 106 (7%) | 892 | 54 (6%) | 658 | 52 (8%) | 0.15 |
Diabetes mellitus | 1550 | 271 (17%) | 892 | 143 (16%) | 658 | 128 (19%) | 0.080 |
Chronic obstructive pulmonary disease | 1550 | 171 (11%) | 892 | 102 (11%) | 658 | 69 (10%) | 0.56 |
Chronic renal disease | 1550 | 162 (10%) | 892 | 58 (7%) | 658 | 104 (16%) | < 0.0001 |
Chronic liver disease | 1550 | 98 (6%) | 892 | 49 (5%) | 658 | 49 (7%) | 0.12 |
Active or recent malignant disease | 1550 | 186 (12%) | 892 | 77 (9%) | 658 | 109 (17%) | < 0.0001 |
Causes for admission | 1551 | 892 | 659 | < 0.0001 | |||
Cardiac causes of admission | 221 (14%) | 150 (17%) | 71 (11%) | ||||
Hemorrhagic shock* | 83 (5%) | 10 (1%) | 73 (11%) | ||||
Acute respiratory failure | 299 (19%) | 204 (23%) | 95 (14%) | ||||
Neurologic causes of admission | 240 (15%) | 200 (22%) | 40 (6%) | ||||
Others | 96 (6%) | 45 (5%) | 51 (8%) | ||||
Polytrauma | 86 (6%) | 38 (4%) | 48 (7%) | ||||
Post-surgery | 156 (10%) | 73 (8%) | 83 (13%) | ||||
Sepsis | 370 (24%) | 172 (19%) | 198 (30%) | ||||
Severity scores | |||||||
SAPS II score | 1550 | 46 (34–60) | 891 | 46 (34–59) | 659 | 46 (35–61) | 0.085 |
SOFA score | 1146 | 7 (4–10) | 633 | 7 (4–10) | 513 | 8 (5–11) | < 0.0001 |
Management | |||||||
Renal replacement therapy | 1551 | 283 (18%) | 892 | 102 (11%) | 659 | 181 (27%) | < 0.0001 |
Red blood cell transfusion | 1551 | 659 (42%) | 892 | 0 (0%) | 659 | 659 (100%) | < 0.0001 |
Platelets transfusion | 1551 | 223 (14%) | 892 | 20 (2%) | 659 | 203 (31%) | < 0.0001 |
Number of red blood transfusions | 1551 | 0 (0–3) | 892 | 0 (0–0) | 659 | 4 (2–7) | < 0.0001 |
Outcomes | |||||||
Length of stay in ICU (days) | 1551 | 12 (7–21) | 892 | 10 (6–16) | 659 | 16 (9–27) | < 0.0001 |
One-year mortality | 1551 | 312 (20%) | 892 | 141 (16%) | 659 | 171 (26%) | < 0.0001 |