| Unadjusted analysis | Adjusted analysisb | ||||
---|---|---|---|---|---|---|
Multiple imputation analysisc | Complete case-analysis | |||||
cHR (95%CI) | P Value | cHR (95%CI) | P Value | cHR (95%CI) | P Value | |
VAP | ||||||
 Overall effect |  | 0.13a |  | 0.082a |  | 0.056a |
 At day 2 | 0.43 (0.15–1.17) |  | 0.47 (0.17–1.31) |  | 0.43 (0.14–1.24) |  |
 At day 7 | 0.86 (0.58–1.28) |  | 0.95 (0.63–1.42) |  | 0.95 (0.63–1.44) |  |
 At day 14 | 1.34 (0.92–1.94) |  | 1.48 (1.01–2.16) |  | 1.59 (1.05–2.38) |  |
 At day 21 | 1.75 (0.99–3.08) |  | 1.94 (1.09–3.46) |  | 2.16 (1.16–4.02) |  |
28-day mortality | 2.01 (1.46–2.75) |  < 0.0001 | 1.67 (1.20–2.33) | 0.002 | 1.47 (1.02–2.10) | 0.034 |
MV duration | 1.14 (0.89–1.45) | 0.30 | 1.25 (1.01–1.54) | 0.036 | 1.18 (0.88–1.56) | 0.25 |
Length of ICU stay | 0.71 (0.54–0.95) | 0.017 | 1.00 (0.80–1.24) | 0.99 | 0.77 (0.56–1.07) | 0.12 |