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Fig. 2 | Critical Care

Fig. 2

From: Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the FEISTY trial

Fig. 2

Clots formed post cryoprecipitate have increased fibre density. A Plasma clots were formed from pooled normal plasma (PNP) or patient plasma pre- and post-cryoprecipitate (cryo) or fibrinogen concentrate (Fg-C) transfusion. Alexa Fluor 488 labelled fibrinogen was incorporated to visualise the fibrin network by confocal microscopy. Representative images of nā€‰=ā€‰3 per cohort. Clots were formed in duplicate. B number of fibres and C fibre length were calculated using Diameter J software. Three areas were analysed per clot. **pā€‰<ā€‰0.01, ***pā€‰<ā€‰0.001, ****pā€‰<ā€‰0.0001

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