Variable | All HABSI (n = 829) | COVID-19 patient (n = 252) | Non-COVID-19 patient (n = 577) | p value |
---|---|---|---|---|
Previous antibiotics: | ||||
Antimicrobials received within the 7 days prior HABSI | 622 (75) | 204 (81) | 418 (72.4) | 0.0092 |
Source of infection: | ||||
Intravascular catheter | 257 (31) | 74 (29.4) | 183 (31.7) | 0.50 |
Respiratory tract | 251 (30.3) | 101 (40.1) | 150 (26) | < 0.0001 |
Primary HABSI | 163 (19.7) | 64 (25.4) | 99 (17.2) | 0.0060 |
Intra-abdominal tract | 75 (9) | 3 (1.2) | 72 (12.5) | < 0.0001 |
Bones and soft tissues | 43 (5.2) | 5 (2) | 38 (6.6) | 0.0060 |
Urinary tract | 35 (4.2) | 8 (3.2) | 27 (4.7) | 0.32 |
Other (endocarditis, mediastinitis, central nervous system) | 28 (3.4) | 4 (1.6) | 24 (4.2) | 0.059 |
Multiple first sources of infection | 23 (2.8) | 7 (2.8) | 16 (2.8) | 0.997 |
Microorganism group: | ||||
Gram-positive bacteria | 285 (34.4) | 100 (39.7) | 185 (32.1) | 0.033 |
Resistant* Gram-positive bacteria | 108 (13) | 32 (12.7) | 76 (13.2) | 0.85 |
Gram-negative bacteria | 505 (60.9) | 151 (59.9) | 354 (61.4) | 0.70 |
DTR Gram-negative bacteria | 124 (15) | 49 (19.4) | 75 (13) | 0.017 |
Fungi | 79 (9.5) | 19 (7.5) | 60 (10.4) | 0.20 |
Anaerobic bacteria | 16 (1.9) | 1 (0.4) | 15 (2.6) | 0.050 |
Polymicrobial HABSI | 97 (11.7) | 37 (14.7) | 60 (10.4) | 0.078 |