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Fig. 5 | Critical Care

Fig. 5

From: Systemic interleukin-6 inhibition ameliorates acute neuropsychiatric phenotypes in a murine model of acute lung injury

Fig. 5

Lung inflammation, cerebral IL-6, and cerebral TNF-α positively and significantly correlate with amygdalar and hippocampal CC3 after IL-6 inhibition. A Regression analysis between the percent of PMNs in bronchoalveolar lavage fluid with amygdalar CC3. SB group is indicated in blue and VILI + Saline in green, VILI + α-IL-6 in red, and VILI + α-IL-6-receptor in brown. Significance (p) and fitness (r2) values are indicated. B Regression analysis between the percent of PMNs in bronchoalveolar lavage fluid with hippocampal CC3. C–D Regression analysis shows a direct and significant relationship between IL-6 and CC3, and TNF-α and CC3 in amygdala and hippocampus

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Critical Care

ISSN: 1364-8535