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Table 1 Characteristics of the cohort with hospital-onset sepsis according to the operating hour of the rapid response team

From: Mortality of patients with hospital-onset sepsis in hospitals with all-day and non-all-day rapid response teams: a prospective nationwide multicenter cohort study

Variable

All-day group (n = 206)

Non-all-day group (n = 199)

P value

Age, year, mean ± SD

63.2 ± 14.1

66.3 ± 15.1

0.034

Sex, male, n (%)

140 (68.0)

122 (61.3)

0.161

BMI, kg/m2, mean ± SD

21.9 (3.7)

22.2 (3.9)

0.311

CCI, mean ± SD

5.4 (2.7)

5.6 (2.8)

0.582

Comorbidities, n (%)

   

 Cardiovascular disease

33 (16.0)

24 (12.1)

0.252

 Chronic respiratory disease

20 (9.7)

25 (12.6)

0.361

 Chronic neurologic disease

21 (10.2)

38 (19.1)

0.011

 Chronic liver disease

23 (11.2)

31 (15.6)

0.192

 Diabetes

62 (30.1)

58 (29.1)

0.834

 Chronic renal disease

20 (9.7)

25 (12.6)

0.361

 Connective tissue disease

1 (0.5)

4 (2.0)

0.209

 Immunosuppressed

10 (4.9)

13 (6.5)

0.466

 Hematologic malignancy

46 (22.3)

38 (19.1)

0.422

 Solid cancer

105 (51.0)

80 (40.2)

0.030

Suspected site of infection, n (%)*

   

 Pulmonary

63 (30.6)

82 (41.2)

0.026

 Gastrointestinal

83 (40.3)

55 (27.6)

0.007

 Urinary

15 (7.3)

26 (13.1)

0.054

 Skin/soft tissue

11 (5.3)

4 (2.0)

0.076

 Other site**

38 (18.4)

41 (20.6)

0.584

Positive blood cultures, n (%)

66 (32.0)

50 (25.1)

0.124

 MRSA

0 (0.0)

4 (2.0)

0.057

 MDR GNB

4 (1.9)

2 (1.0)

0.685

 VRE

21 (10.2)

9 (4.5)

0.029

Septic shock by Sepsis 3, n (%)

108 (52.4)

58 (29.1)

< 0.001

 SOFA score, mean ± SD

6.6 ± 2.7

6.3 ± 3.3

0.091

 Serum lactate, mmol/l, mean ± SD

4.1 ± 3.4

3.6 ± 2.8

0.145

  1. SD = standard deviation, BMI = body mass index, CCI = Charlson comorbidity index, MDR = multidrug resistant, SOFA = sequential organ failure assessment
  2. *13 patients—4 in the all-day group and 9 in the non-all-day group—had multiple sites of infection
  3. **Other sites of infection include blood-stream infection, catheter-associated infection, and unknown