Discomfort improvement for critically ill patients using electronic relaxation devices: results of the cross-over randomized controlled trial E-CHOISIR (Electronic-CHOIce of a System for Intensive care Relaxation)

Table 3 Multivariate mixed-effect model—benefits of specific electronic relaxation techniques compared to standard relaxation

	Gain estimate	p		Gain estimate	p
Overall discomfort			ANI
Music care^®	− 0.4	0.25	Music care^®	0.7	0.87
VR Deepsen^®	− 0.1	0.85	VR Deepsen^®	8.5	0,07
VR Healthy mind^®	− 0.8	*0.01*	VR Healthy mind^®	13	*0.006*
Standard	0		Standard	0
Pain			Heart rate
Music care^®	− 0.3	0.23	Music care^®	0.1	0.39
VR Deepsen^®	− 0.3	0.19	VR Deepsen^®	− 0.5	0.75
VR Healthy mind^®	− 0.8	*0.001*	VR Healthy mind^®	1.0	0.47
Standard	0		Standard	0
Anxiety			Systolic blood pressure
Music care^®	− 0.1	0.7	Music care^®	2.2	0.7
VR Deepsen^®	− 0.9	*0.001*	VR Deepsen^®	2.1	0.5
VR Healthy mind^®	− 0.8	*0.004*	VR Healthy mind^®	2.2	0.8
Standard	0		Standard
Thirst			Diastolic blood pressure
Music care^®	0.0	0.88	Music care^®	− 2	0.2
VR Deepsen^®	0.0	0.93	VR Deepsen^®	1.8	0.2
VR Healthy Mind^®	− 0.3	0.45	VR Healthy Mind^®	− 0.3	0.8
Standard	0		Standard	0
Dyspnea			Respiratory rate
Music care^®	− 0.6	0.06	Music care^®	− 1	0.4
VR Deepsen^®	− 0.3	0.42	VR Deepsen^®	0.5	0.65
VR Healthy mind^®	− 0.3	0.39	VR Healthy mind^®	− 2	0.12
Standard	0		Standard	0
Lack of rest feeling
Music care^®	− 0.7	0.26
VR Deepsen^®	− 1.6	*0.01*
VR Healthy mind^®	− 1.2	0.07
Standard	0

This multivariable mixed model was performed to compare different electronic devices between them, dealing with multiple assessments, different orders of relaxation sessions, and significant patient characteristics. The estimate of the improvement in the self-reported assessment of symptoms’ intensity, Analgesia/Nociception Index (ANI), and physiological variables was reported for each relaxation device, compared to the standard relaxation session
The Italic, bold values are for significant p values

ISSN: 1364-8535