Table 4 Comparison of alveolar collapse and overdistention between PEEP groups
Total (n = 75) | PEEPlower (n = 23) | PEEPequal (n = 28) | PEEPhigher (n = 24) | p value | |
|---|---|---|---|---|---|
Alveolar collapse | |||||
Collapse at PEEPset | 6.1 (3.6) | 5.8 (3.9) | 6.8 (3.9) | 5.5 (2.8) | 0.56 |
Collapse at PEEP 12 cmH2O | 17.8 (10.8) | 10.2 (7.9) | 17.1 (8.8) | 24.5 (11.4) | < 0.001* |
Collapse at PEEP 24 cmH2O | 0.0 [0.0–0.6] | 0.0 [0.0–0.2] | 0.0 [0.0–0.1] | 0.4 [0.0–1.1] | 0.12 |
Collapse diff (PEEP 24- > 12) | 17.3 (10.3) | 9.8 (7.7) | 16.3 (8.0) | 24.8 (10.2) | < 0.001* |
Overdistention | |||||
Overdistention at PEEPset | 11.3 [5.4–15.4] | 8.8 [4.5–13.1] | 10.1 [5.9–15.0] | 12.8 [10.2–17.2] | 0.20 |
Overdistention at PEEP 12 cmH2O | 5.1 [2.1–9.2] | 9.6 [4.9–15.5] | 3.3 [1.4–6.1] | 5.1 [3.6–7.7] | 0.062 |
Overdistention at PEEP 24 cmH2O | 31.3 [26.3–38.4] | 37.5 [31.1–56.0] | 30.8 [26.3–38.8] | 29.6 [20.4–32.6] | 0.025* |
Hyperdistention diff (PEEP 24- > 12) | − 25.6 [− 31.6–17.0] | − 28.3 [− 43.2–22.2] | − 26.5 [− 35.0–19.1] | − 22.7 [− 28.0–14.0] | 0.13 |