Table 2 CEUS parameters for healthy controls and patients with severe AKI and non-severe AKI, between groups and within groups over time
Timepoint | D0 | D1 | D2 | D4 | Significance (p) |
|---|---|---|---|---|---|
mTT (s) | |||||
HC | 2.09 (1.78–2.14) |  |  |  |  |
Severe | 10.2 (6.54–23.2) | 11.3 (6.24–19.9) | 10.7 (6.02–20.2) | 7.7 (4.54–13.2) | 0.11 |
Non-severe | 5.54 (4.65–6.47) | 5.03 (4.43–8.06) | 4.81 (4.1–7.61) | 4.57 (3.14–5.88) | 0.45 |
significance |  < 0.05 (all groups) |  < 0.05 |  < 0.05 |  < 0.05 |  |
WiR (a.u.) | |||||
HC | 2040 (1868–2196) |  |  |  |  |
Severe | 409 (238–606) | 583 (291–899) | 555 (342–876) | 558 (304–1278) | 0.21 |
Non-severe | 1203 (790–1489) | 833 (496–2438) | 1152 (649–1830) | 1274 (1119–1829) | 0.90 |
Significance |  < 0.05 (all groups) |  < 0.05 |  < 0.05 |  < 0.05 |  |
PI (a.u.) | |||||
HC | 2888 (2603–3077) |  |  |  |  |
Severe | 485 (302–829) | 690 (396–1266) | 791 (390–1130) | 732 (410–1676) | 0.36 |
Non-severe | 1758 (1126–2100) | 1193 (649–2983) | 1479 (942–2734) | 1856 (1538–2595) | 0.89 |
Significance |  < 0.05 (all groups) |  < 0.05 |  < 0.05 |  < 0.05 |  |
RBV (a.u.) | |||||
HC | 5644 (5337–5917) |  |  |  |  |
Severe | 5123 (3604–7209) | 6572 (4397–9102) | 6940 (4950–8642) | 5722 (4155–7463) | 0.18 |
Non-severe | 8538 (5659–11,030) | 5630 (4523–9558) | 8308 (5978–10,770) | 8025 (7549–9553) | 0.95 |
Significance |  < 0.05 (severe vs. non-severe) | 0.97 | 0.43 |  < 0.05 |  |