Skip to main content

Table 1 Characteristics of patients at study enrolment based on the degree of acute kidney injury

From: Decreased renal cortical perfusion, independent of changes in renal blood flow and sublingual microcirculatory impairment, is associated with the severity of acute kidney injury in patients with septic shock

 

Severe AKI

Non-severe AKI

Control

Significance (p)

Age

63 (46–73)

67 (61–71)

34 (30–36)

0.21 patient groups; < 0.001 vs. controls

Female (%)

38

39

58

0.45

SOFA

15.3 ± 3.3

9.3 ± 1.9

 

 < 0.001

Norepinephrine dose (mcg/kg/min)

0.34 (0.26–0.51)

0.21 (0.14–0.3)

 

0.009

Additional inotropes n(%)

18 (49)

1 (8)

 

0.02

Lactate (mmol/l)

3.9 (2.7–7.4)

2.7 (1.9–3.5)

 

0.03

Base Excess (mEq/l)

−6.3 ± 4.2

−4.0 ± 4.3

 

0.14

Haemoglobin (mg/dl)

93 (81–111)

108 (99–115)

 

0.07

C Reactive protein (mg/dl)

150 (99–279)

256 (160–293)

 

0.25

White cell count (× 109/L)

11.0 (7.1–25.6)

13.2 (9.4–14.5)

 

0.92

PcvCO2-PaCO2 (kPa)

0.89 (0.54–1.16)

0.875 (0.748–1.11)

 

0.59

ScvO2 (%)

68 ± 14.4

70 ± 7.8

 

0.72

Mean Arterial Pressure (mmHg)

69 (-62–74)

70 (68–73)

 

0.84

Heart rate

100 ± 18

91 ± 15

 

0.11

CKD stage 2–3 (n)

5

0

 

0.40

Hypertension (n)

12

7

 

0.27

Diabetes (n)

9

4

 

0.89

  1. SOFA Serial Organ Failure Assessment, ScvO2 central venous oxygen saturation, PcvCO2 central venous partial pressure carbon dioxide, PaCO2 arterial partial pressure carbon dioxide