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Table 4 Additional results of renal multiparametric MRI

From: Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study

 

AKI

n

NO AKI

n

Healthy volunteers

n

Perfusion

      

Global perfusion (ml/100 g/min)

168 [142–216]

10

202 [174–235]

9

220 [174–242]

12

Regional perfusion ratio (cortex/medulla)

2.4 [2.2–3.3]

10

2.2 [1.7–3.4]

7

  

Resistance index*

0.90 [0.82–0.93]

10

0.79 [0.75–0.86]

8

  

Structure and regional water diffusion

      

Total kidney volume (ml)

356 [331–437]

10

390 [359–447]

9

403 [345–430]

12

T1 cortex (ms)†

1560 [1524–1638]

8

1522 [1497–1638]

8

1459 [1400–1525]

12

T1 medulla (ms)

1838 [1732–1872]

8

1792 [1695–1870]

8

1732 [1661–1850]

12

T2 cortex (ms)

120 [113–134]

8

124 [119–141]

8

  

DWI cortex ADC (× 10–3 mm2/s)

1.9 [1.9–2.1]

8

2.1 [1.9–2.1]

8

  

DWI medulla ADC (× 10–3 mm2/s)

1.9 [1.9–2.0]

8

2.1 [1.8–2.1]

8

  

DWI cortex D (× 10–3 mm2/s)

1.8 [1.7–1.9]

8

1.9 [1.7–2]

8

  

DWI cortex D* (× 10–3 mm2/s)

26 [23–29]

8

27 [24–28]

8

  

DWI cortex fp

0.13 [0.11–0.15]

8

0.13 [0.11–0.14]

8

  

DWI medulla D (× 10–3 mm2/s)

1.8 [1.7–1.9]

8

1.9 [1.7–2]

8

  

DWI medulla D* (× 10–3 mm2/s)

26 [23–17]

8

27 [26–28]

8

  

DWI medulla FP

0.14 [0.11–0.17]

8

0.15 [0.12–0.16]

8

  
  1. Results of renal multiparametric MRI in 19 patients treated in ICU for respiratory failure due to COVID-19 with AKI or NO AKI, and 12 healthy volunteers of similar age. Data presented as median [quartile range]. Significant differences from Mann–Whitney U test between AKI and NO AKI groups are indicated by * if p < 0.05. Significant differences from one way Kruskal–Wallis ANOVA between all groups are indicated by † if p < 0.05 and ††† if p < 0.001. Valid numbers of MRI examinations are specified for each measure and group. Additional results are presented in Fig. 1
  2. T1 longitudinal relaxation time, T2 transverse relaxation time, DWI diffusion weighted imaging, ADC apparent diffusion coefficient, D pure diffusion, D* pseudodiffusion, fp perfusion fraction