Fig. 2
Physiological outcomes after each step in the trial. The proportion of patients who met lung and diaphragm-protective (LDP) targets at the end of each study phase in those not receiving VV-ECMO (A) and those receiving VV-ECMO (B). Below the stacked bar plots, the corresponding distributions of respiratory effort (ΔPes) and lung-distending pressure (ΔPL,dyn) are shown. Error bars represent 25th and 75th percentiles with median (circle). *Not all eligible patients received partial neuromuscular blockade due to decision of the attending physician. LDP: lung and diaphragm protection, VV ECMO: veno-venous extracorporeal membrane oxygenation, pNMBA: partial neuromuscular blockade, ∆Pes: esophageal pressure swing, ∆PL,dyn: dynamic transpulmonary driving pressure