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Table 2 Performance of ddPCR results for targeted organisms

From: Clinical validation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections in ICU practice: a promising diagnostic tool

 

BC+/ddPCR+, n*

BC+/ddPCR−, n**

BC−/ddPCR+, n

BC−/ddPCR−, n***

Pathogens (all)

44

11

231

251

Acinetobacter baumannii

3

0

35

–

Klebsiella pneumoniae

9

1

45

–

Escherichia coli

5

0

26

–

Pseudomonas aeruginosa

5

1

31

–

Staphylococcus aureus

3

1

6

–

Enterococcus faecalis

3

0

9

–

Enterococcus faecium

5

1

39

–

Streptococcus pneumoniae

0

0

0

–

Candida parapsilosis

1

4

9

–

Candida tropicalis

1

0

4

–

Candida glabrata

5

1

8

–

Candida albicans

4

2

19

–

  1. *The results of BC+/ddPCR+, BC+/ddPCR−, and BC−/ddPCR+ were calculated according to pathogens. For the BC+/ddPCR+ group, there were polymicrobial infections in 11 cases by ddPCR testing
  2. **In four samples of the 11 BC-positive episodes, ddPCR testing showed difference with the BC results, which were comprehensively analyzed combined with clinical presentation
  3. ***Episode (sample) with the
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Critical Care

ISSN: 1364-8535