| All patients(n = 7784) | Missing, n (%) |
---|---|---|
Age (years) | 65.0 (54.0–76.0) | 0 (%) |
Male (gender) | 4452 (57.2) | 0 (%) |
Weight (kg) | 80.0 (66.7–97.0) | 202 (2.6%) |
Height (cm) | 170.0 (163.0–178.0) | 1384 (17.8%) |
Admission type, n (%) | Â | 0 (%) |
Medical | 4714 (60.6) | Â |
Surgical elective | 153 (2.0) | Â |
Surgical urgent | 1830 (23.5) | Â |
Other | 1087 (14.0) | Â |
Ethnicity, n (%) | Â | 0 (%) |
White | 4695 (60.3) | Â |
Black | 823 (10.6) | Â |
Hispanic | 266 (3.4) | Â |
Other | 1787 (23.0) | Â |
Elixhauser comorbidity score | 6.0 (4.0–8.0) | 0 (%) |
Severity of illness | Â | Â |
GCS | 14.6 (1.1) | 4 (0.1%) |
SAPS II | 43.0 (33.0–54.0) | 0 (%) |
OASIS | 42.0 (36.0–47.2) | 0 (%) |
SOFA | 3.0 (2.0–5.0) | 820 (10.5%) |
Use of vasopressor (1 st 24Â h) | 4462 (57.3) | 0 (%) |
Initial diagnosis, n (%) | Â | 0 (%) |
Sepsis | 6964 (89.5) | Â |
Acute respiratory failure | 3938 (50.6) | Â |
Cardiac arrest | 493 (6.3) | Â |
Vital signs (1 st 24Â h) | Â | Â |
Heart rate (bpm) | 86.5 (75.2–99.1) | 1 (0.0%) |
MAP (mmHg) | 75.8 (70.4–82.6) | 1 (0.0%) |
Temperature (℃) | 37.0 (36.7–37.4) | 463 (5.9%) |
Parameters of mechanical ventilation (1 st 24Â h) | Â | Â |
TWA-FiO2 | 0.50 (0.42–0.59) | 6 (0.1%) |
Total respiratory rate (bpm) | 20.1 (17.5–23.0) | 12 (0.2%) |
Tidal volume (ml/kg PBW) | 7.0 (6.4–7.8) | 1385 (17.8%) |
PEEP (cmH2O) | 6.1 (5.1–8.1) | 2 (0.0%) |
Plateau pressure (cmH2O) | 18.8 (16.1–22.0) | 297 (3.8%) |
Use of NMBA, n (%) | 413 (5.3) | 0 (%) |
Laboratory data (1 st 24Â h) | Â | Â |
pH | 7.4 (7.3–7.4) | 1221 (15.7%) |
PaCO2 (mmHg) | 39.8 (35.0–45.0) | 1221 (15.7%) |
TWA-PaO2 (mmHg) | 130.5 (100.5–171.0) | 1240 (15.9%) |
Lactate (mmol/L) | 2.0 (1.3–3.3) | 1829 (23.5%) |
Bicarbonate (mmol/L) | 22.2 (19.5–25.3) | 46 (0.6%) |
Fluid balance in the first 24 h (L) | 1.54 (− 0.24–4.59) | 90 (1.2%) |
Clinical outcomes | Â | Â |
28-day mortality, n (%) | 2044 (26.3) | 0 (%) |
In-hospital mortality, n (%) | 2154 (27.7) | 0 (%) |
Alive and VFDs (days) | 19.9 (0.0–24.2) | 0 (%) |
Length of ICU stay (days) | 7.8 (4.9–13.1) | 0 (%) |
Length of hospital stay (days) | 14.0 (8.0–22.0) | 0 (%) |