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Table 2 Comparison of characteristics of patients with high-mortality phenotypes in each cohort

From: Development of clinical phenotypes and biological profiles via proteomic analysis of trauma patients

Clinical phenotype D-8 V-8 B-8 Overall p value
Number of patients 2178 1241 9 3428
Age, years, median [IQR] 66 [46–77] 67 [47–79] 66 [52–79] 66 [46–78] 0.122
Male gender, no. (%) 1502 (69) 856 (69) 9 (100) 2367 (69) 0.132
CPS (median [IQR]) 1 [1–1] 1 [1–1] 1 [0–1] 1 [1–1]  < 0.001
Respiratory rate, median [IQR] 20 [16–25] 20 [16–25] 21 [17–27] 20 [16–25] 0.793
Heart rate, median [IQR] 92 [76–113] 98 [80–118] 108 [98–126] 94 [78–115]  < 0.001
Systolic blood pressure, median [IQR] 138 [109–167] 141 [111–169] 169 [152–205] 140 [110–168] 0.029
Body temperature, median [IQR] 36.0 [35.3–36.5] 36.1 [35.5–36.6] 35.8 [35.1–36.4] 36.0 [35.4–36.5]  < 0.001
Glasgow coma scale, median [IQR] 3 [3–6] 3 [3–5] 3 [3–3] 3 [3–6] 0.004
Head and Cervical AIS, median [IQR] 5 [4, 5] 5 [4, 5] 5 [5–5] 5 [4, 5] 0.002
Face AIS, median [IQR] 0 [0–0] 0 [0–0] 0 [0–0] 0 [0–0] 0.662
Chest AIS, median [IQR] 0 [0–3] 0 [0–3] 0 [0–0] 0 [0–3] 0.003
Abdomen AIS, median [IQR] 0 [0–0] 0 [0–0] 0 [0–0] 0 [0–0] 0.229
Extremities AIS, median [IQR] 0 [0–2] 0 [0–2] 1 [0–2] 0 [0–2] 0.748
External AIS, median [IQR] 0 [0–0] 0 [0–0] 0 [0–0] 0 [0–0]  < 0.001
ISS, median [IQR] 25 [21–34] 26 [25–36] 29 [25–30] 25 [22–35]  < 0.001
RTS, median [IQR] 4.09 [4.09–5.21] 4.09 [4.09–5.03] 4.09 [4.09–4.09] 4.09 [4.09–5.03] 0.102
TRISS-PS, median [IQR] 0.45 [0.26–0.67] 0.40 [0.21–0.63] 0.35 [0.21–0.39] 0.43 [0.24–0.65]  < 0.001
Survival, no. (%) 1119 (51.4) 647 (52.1) 5 (55.6) 1771(51.7) 0.888
  1. IQR interquartile range, CPS Charlson polypharmacy scale, AIS abbreviated injury scale, ISS injury severity scale, RTS revised trauma score, TRISS-PS Trauma and Injury Severity Score and Probability of Survival