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Table 2 Comparison of characteristics of patients with high-mortality phenotypes in each cohort

From: Development of clinical phenotypes and biological profiles via proteomic analysis of trauma patients

Clinical phenotype

D-8

V-8

B-8

Overall

p value

Number of patients

2178

1241

9

3428

Age, years, median [IQR]

66 [46–77]

67 [47–79]

66 [52–79]

66 [46–78]

0.122

Male gender, no. (%)

1502 (69)

856 (69)

9 (100)

2367 (69)

0.132

CPS (median [IQR])

1 [1–1]

1 [1–1]

1 [0–1]

1 [1–1]

 < 0.001

Respiratory rate, median [IQR]

20 [16–25]

20 [16–25]

21 [17–27]

20 [16–25]

0.793

Heart rate, median [IQR]

92 [76–113]

98 [80–118]

108 [98–126]

94 [78–115]

 < 0.001

Systolic blood pressure, median [IQR]

138 [109–167]

141 [111–169]

169 [152–205]

140 [110–168]

0.029

Body temperature, median [IQR]

36.0 [35.3–36.5]

36.1 [35.5–36.6]

35.8 [35.1–36.4]

36.0 [35.4–36.5]

 < 0.001

Glasgow coma scale, median [IQR]

3 [3–6]

3 [3–5]

3 [3–3]

3 [3–6]

0.004

Head and Cervical AIS, median [IQR]

5 [4, 5]

5 [4, 5]

5 [5–5]

5 [4, 5]

0.002

Face AIS, median [IQR]

0 [0–0]

0 [0–0]

0 [0–0]

0 [0–0]

0.662

Chest AIS, median [IQR]

0 [0–3]

0 [0–3]

0 [0–0]

0 [0–3]

0.003

Abdomen AIS, median [IQR]

0 [0–0]

0 [0–0]

0 [0–0]

0 [0–0]

0.229

Extremities AIS, median [IQR]

0 [0–2]

0 [0–2]

1 [0–2]

0 [0–2]

0.748

External AIS, median [IQR]

0 [0–0]

0 [0–0]

0 [0–0]

0 [0–0]

 < 0.001

ISS, median [IQR]

25 [21–34]

26 [25–36]

29 [25–30]

25 [22–35]

 < 0.001

RTS, median [IQR]

4.09 [4.09–5.21]

4.09 [4.09–5.03]

4.09 [4.09–4.09]

4.09 [4.09–5.03]

0.102

TRISS-PS, median [IQR]

0.45 [0.26–0.67]

0.40 [0.21–0.63]

0.35 [0.21–0.39]

0.43 [0.24–0.65]

 < 0.001

Survival, no. (%)

1119 (51.4)

647 (52.1)

5 (55.6)

1771(51.7)

0.888

  1. IQR interquartile range, CPS Charlson polypharmacy scale, AIS abbreviated injury scale, ISS injury severity scale, RTS revised trauma score, TRISS-PS Trauma and Injury Severity Score and Probability of Survival