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Table 1 Baseline characteristics of the patients in all three cohorts

From: Development of clinical phenotypes and biological profiles via proteomic analysis of trauma patients

Variables

Derivation cohort

Validation cohort

Osaka University cohort

Overall

Number of patients

42,780

28,258

171

71,209

Age, years, median [IQR]

62 [38–77]

65 [42–79]

50 [34–71]

63 [40–78]

Male gender, no. (%)

27,545 (64.4)

17,934 (63.5)

128 (74.9)

45,607 (64.0)

CPS, median [IQR]

1 [1–1]

1 [1, 2]

0 [0–1]

1 [1–1]

Respiratory rate, median [IQR]

20 [17–24]

20 [17–24]

21 [18–26]

20 [17–24]

Heart rate, median [IQR]

83 [72–96]

83 [72–96]

90 [74–108]

83 [72–96]

Systolic blood pressure, median [IQR]

138 [119–158]

139 [120–160]

139 [119–161]

138 [119–159]

Body temperature (℃), median [IQR]

36.5 [36.0–36.9]

36.5 [36.1–36.9]

36.5 [36.0–36.9]

36.5 [36.0–36.9]

Glasgow Coma Scale, median [IQR]

15 [14, 15]

15 [14, 15]

14 [12–15]

15 [14, 15]

Head & Cervical AIS, median [IQR]

1 [0–4]

1 [0–4]

1 [0–4]

1 [0–4]

Face AIS, median [IQR]

0 [0–0]

0 [0–0]

0 [0–0]

0 [0–0]

Chest AIS, median [IQR]

0 [0–2]

0 [0–2]

0 [0–3]

0 [0–2]

Abdomen AIS, median [IQR]

0 [0–0]

0 [0–0]

0 [0–1]

0 [0–0]

Extremities AIS, median [IQR]

2 [0–3]

2 [0–3]

1 [0–2]

2 [0–3]

External AIS, median [IQR]

0 [0–0]

0 [0–0]

0 [0–0]

0 [0–0]

ISS, median [IQR]

13 [9–20]

13 [9–20]

17 [6–26]

13 [9–20]

RTS, median [IQR]

7.84 [7.55–7.84]

7.84 [7.84–7.84]

7.84 [6.90–7.84]

7.84 [7.55–7.84]

TRISS-PS, median [IQR]

0.97 [0.93–0.99]

0.97 [0.93–0.99]

0.97 [0.84–0.99]

0.97 [0.93–0.99]

Survival, no. (%)

40,344 (94.3)

26,753 (94.7)

161 (94.2)

67,258 (94.5)

  1. IQR interquartile range, CPS Charlson polypharmacy scale, AIS abbreviated injury scale, ISS injury severity scale, RTS revised trauma score, TRISS-PS, Trauma and Injury Severity Score and Probability of Survival