Long-term cognitive functioning is impaired in ICU-treated COVID-19 patients: a comprehensive controlled neuropsychological study

Table 4 Hierarchical regression of ICU-specific variables in predicting the total neuropsychological score

	Included variables	R	R²	Adj R²	AIC	Overall model test		Model comparison
	Included variables	R	R²	Adj R²	AIC	F (df)	p	ΔR²	F (df)	p
1	Age, sex, education	0.670	0.448	0.424	435	18.2 (3.67)	< .001
2	+ CCI	0.718	0.516	0.487	427	17.6 (4.66)	< .001	0.06771	9.235 (1.66)	0.003
3	+ Proning	0.720	0.518	0.481	429	14.0 (5.65)	< .001	0.00212	0.286 (1.65)	0.594
4	+ IMV-duration	0.731	0.535	0.491	429	12.3 (6.64)	< .001	0.01648	2.267 (1.64)	0.137
5	+ Delirium	0.740	0.548	0.498	429	10.9 (7.63)	< .001	0.01365	1.904 (1.63)	0.173

Statistical significance marked in bold
All models include age, sex, and education. Other variables are added one by one in models 2–5. R² Coefficient of determination, Adj R² Adjusted R², AIC Akaike information criterion, df Degrees of freedom, ΔR² Change in R², CCI Charlson comorbidity index, IMV Invasive mechanical ventilation

ISSN: 1364-8535