Hemodynamic instability was annotated by hemodynamic interventions under any of the following criteria | |
---|---|
US Cohort* | TPEVGH Cohort** |
Administration of any quantity of any of the following inotropic and vasopressor medications: | Administration of any quantity of any of the following inotropic and vasopressor medications: |
1. Dobutamine | 1. Dobutamine |
2. Dopamine | 2. Dopamine |
3. Epinephrine | 3. Epinephrine |
4. Levophed | 4. Levophed |
5. Neosynephrine | 5. Norepinephrine |
6. Norepinephrine | 6. Phenylephrine |
7. Phenylephrine | 7. Vasopressin |
8. Vasopressin | |
Administration of fluid therapy (colloid or crystalloid) in the following dosages: | Administration of fluid therapy (colloid or crystalloid) in the following dosages: |
1. 2400 cc in 8 h | 1. The same as US |
2. 3000 cc in 12 h | 2. 25% Albumin 200 cc with 2 h |
Administration of packed red blood cells (PRBCs) in either of the following dosages: | Administration of packed red blood cells (PRBCs) in either of the following dosages: |
1. 800 cc PRBC over course of 24 h | 1. PRBC > 1500 cc with 24 h |
2. 500 cc in 2 hours followed by fluid therapy within 12 h. (What qualifies as “fluid therapy" is described in this table, titled "Administration of Fluid Therapy.") | 2. PRBC 500 cc + FPP 500 cc + PLT Pheresis 500 cc within 6 h |