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Table 3 Evolution of hemodynamic variables in preload responsive cases and non-responsive cases

From: Tidal volume challenge to predict preload responsiveness in patients with acute respiratory distress syndrome under prone position

Variables EEO6 TVC EEO8 TREND
Baseline for PCCImax* Baseline for PPVmax Baseline for PCCImax* Baseline PCCImax*
Heart rate (beats/min)
Responsive cases 89 ± 20 90 ± 20 90 ± 20 90 ± 21 90 ± 21 91 ± 21 90 ± 21 90 ± 19
Non-responsive cases 81 ± 20 81 ± 20 81 ± 20 81 ± 20 81 ± 20 80 ± 19 82 ± 20 80 ± 20
Systolic arterial pressure (mmHg)
Responsive cases 122 ± 17 126 ± 18 126 ± 19 122 ± 18 121 ± 17 125 ± 18 122 ± 19 144 ± 20abcd
Non-responsive cases 125 ± 18 125 ± 18 124 ± 18 123 ± 17 124 ± 18 124 ± 19 124 ± 17 133 ± 18abcd
Diastolic arterial pressure (mmHg)
Responsive cases 58 ± 8 59 ± 9 60 ± 9 58 ± 9 58 ± 8 59 ± 9 58 ± 9 70 ± 1abcd
Non-responsive cases 56 ± 9 56 ± 9 56 ± 9 55 ± 8 55 ± 9 55 ± 9 56 ± 9 62 ± 9abcd
Mean arterial pressure (mmHg)
Responsive cases 79 ± 11 82 ± 12 82 ± 13 79 ± 11 78 ± 11 81 ± 11 79 ± 12 96 ± 14abcd
Non-responsive cases 80 ± 11 80 ± 11 79 ± 11 78 ± 11 79 ± 11 79 ± 11 79 ± 11 87 ± 12abcd
Pulse pressure (mmHg)
Responsive cases 64 ± 14 66 ± 15 67 ± 15 64 ± 14 63 ± 14 66 ± 15 64 ± 15 74 ± 16abcd
Non-responsive cases 69 ± 16 70 ± 16 69 ± 16 68 ± 16 68 ± 16 69 ± 16 68 ± 15 71 ± 16abcd
Central venous pressure (mmHg)
Responsive cases 8 ± 4 7 ± 4 8 ± 4 8 ± 4 8 ± 4 7 ± 4 7 ± 4 13 ± 5abcd
Non-responsive cases 11 ± 5 10 ± 5 11 ± 5 11 ± 5 11 ± 5 10 ± 5 10 ± 5 16 ± 8abcd
Pulse pressure variation (%)
Responsive cases 9 ± 5a 8 ± 4a 9 ± 4a 13 ± 5ab 12 ± 5ab 11 ± 5ab 9 ± 4ad 9 ± 4acd
Non-responsive cases 5 ± 2 4 ± 2 4 ± 2 6 ± 3b 6 ± 3b 5 ± 3b 4 ± 2d 5 ± 3
PCCI (L/min/m2)
Responsive cases 2.66 ± 0.75a 2.81 ± 0.78a 2.70 ± 0.73a 2.56 ± 0.66a 2.53 ± 0.65a 2.73 ± 0.69a 2.59 ± 0.67a 2.92 ± 0.74abcd
Non-responsive cases 3.35 ± 0.99 3.39 ± 1.00 3.33 ± 0.95 3.25 ± 0.94 3.27 ± 0.97 3.32 ± 0.97 3.43 ± 1.13 3.31 ± 1.01
Intra-abdominal pressure (mmHg)‡
Responsive cases 11 ± 4 11 ± 4 11 ± 4 11 ± 4 11 ± 4 11 ± 4 11 ± 4 11 ± 4
Non-responsive cases 11 ± 4 11 ± 4 11 ± 4 12 ± 4 12 ± 4 11 ± 4c 11 ± 4 10 ± 4 cd
  1. EEO6 end-expiratory occlusion performed at 6 mL/kg tidal volume, EEO8 end-expiratory occlusion performed at 8 mL/kg tidal volume, Max maximal value, PCCI pulse contour cardiac index, TREND Trendelenburg maneuver, TV tidal volume, TVC tidal volume challenge
  2. *variables values collected for the maximal PCCI obtained during EEO6, EEO8 and TREND. variables values collected for the maximal PPV obtained during TVC. available in 78 cases (40 responsive vs. 38 non-responsive cases). ap < 0.05, responsive vs. non-responsive cases; bp < 0.05 compared with EEO6 at the same timepoint; cp < 0.05 compared with TVC at the same timepoint; dp < 0.05 compared with EEO8 at the same timepoint