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Table 3 Evolution of hemodynamic variables in preload responsive cases and non-responsive cases

From: Tidal volume challenge to predict preload responsiveness in patients with acute respiratory distress syndrome under prone position

Variables

EEO6

TVC

EEO8

TREND

Baseline

for PCCImax*

Baseline

for PPVmax†

Baseline

for PCCImax*

Baseline

PCCImax*

Heart rate (beats/min)

Responsive cases

89 ± 20

90 ± 20

90 ± 20

90 ± 21

90 ± 21

91 ± 21

90 ± 21

90 ± 19

Non-responsive cases

81 ± 20

81 ± 20

81 ± 20

81 ± 20

81 ± 20

80 ± 19

82 ± 20

80 ± 20

Systolic arterial pressure (mmHg)

Responsive cases

122 ± 17

126 ± 18

126 ± 19

122 ± 18

121 ± 17

125 ± 18

122 ± 19

144 ± 20abcd

Non-responsive cases

125 ± 18

125 ± 18

124 ± 18

123 ± 17

124 ± 18

124 ± 19

124 ± 17

133 ± 18abcd

Diastolic arterial pressure (mmHg)

Responsive cases

58 ± 8

59 ± 9

60 ± 9

58 ± 9

58 ± 8

59 ± 9

58 ± 9

70 ± 1abcd

Non-responsive cases

56 ± 9

56 ± 9

56 ± 9

55 ± 8

55 ± 9

55 ± 9

56 ± 9

62 ± 9abcd

Mean arterial pressure (mmHg)

Responsive cases

79 ± 11

82 ± 12

82 ± 13

79 ± 11

78 ± 11

81 ± 11

79 ± 12

96 ± 14abcd

Non-responsive cases

80 ± 11

80 ± 11

79 ± 11

78 ± 11

79 ± 11

79 ± 11

79 ± 11

87 ± 12abcd

Pulse pressure (mmHg)

Responsive cases

64 ± 14

66 ± 15

67 ± 15

64 ± 14

63 ± 14

66 ± 15

64 ± 15

74 ± 16abcd

Non-responsive cases

69 ± 16

70 ± 16

69 ± 16

68 ± 16

68 ± 16

69 ± 16

68 ± 15

71 ± 16abcd

Central venous pressure (mmHg)

Responsive cases

8 ± 4

7 ± 4

8 ± 4

8 ± 4

8 ± 4

7 ± 4

7 ± 4

13 ± 5abcd

Non-responsive cases

11 ± 5

10 ± 5

11 ± 5

11 ± 5

11 ± 5

10 ± 5

10 ± 5

16 ± 8abcd

Pulse pressure variation (%)

Responsive cases

9 ± 5a

8 ± 4a

9 ± 4a

13 ± 5ab

12 ± 5ab

11 ± 5ab

9 ± 4ad

9 ± 4acd

Non-responsive cases

5 ± 2

4 ± 2

4 ± 2

6 ± 3b

6 ± 3b

5 ± 3b

4 ± 2d

5 ± 3

PCCI (L/min/m2)

Responsive cases

2.66 ± 0.75a

2.81 ± 0.78a

2.70 ± 0.73a

2.56 ± 0.66a

2.53 ± 0.65a

2.73 ± 0.69a

2.59 ± 0.67a

2.92 ± 0.74abcd

Non-responsive cases

3.35 ± 0.99

3.39 ± 1.00

3.33 ± 0.95

3.25 ± 0.94

3.27 ± 0.97

3.32 ± 0.97

3.43 ± 1.13

3.31 ± 1.01

Intra-abdominal pressure (mmHg)‡

Responsive cases

11 ± 4

11 ± 4

11 ± 4

11 ± 4

11 ± 4

11 ± 4

11 ± 4

11 ± 4

Non-responsive cases

11 ± 4

11 ± 4

11 ± 4

12 ± 4

12 ± 4

11 ± 4c

11 ± 4

10 ± 4 cd

  1. EEO6 end-expiratory occlusion performed at 6 mL/kg tidal volume, EEO8 end-expiratory occlusion performed at 8 mL/kg tidal volume, Max maximal value, PCCI pulse contour cardiac index, TREND Trendelenburg maneuver, TV tidal volume, TVC tidal volume challenge
  2. *variables values collected for the maximal PCCI obtained during EEO6, EEO8 and TREND. †variables values collected for the maximal PPV obtained during TVC. ‡available in 78 cases (40 responsive vs. 38 non-responsive cases). ap < 0.05, responsive vs. non-responsive cases; bp < 0.05 compared with EEO6 at the same timepoint; cp < 0.05 compared with TVC at the same timepoint; dp < 0.05 compared with EEO8 at the same timepoint
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Critical Care

ISSN: 1364-8535