Table 2 Patient and kidney outcomes according to different AKI categories and AKD

(a) Patient outcomes

No AKI

AKI

12 (6.3%)

322 (29.4%)

 < 0.001

17 (8.9%)

350 (32.1%)

 < 0.001

11 (18.3%)

297 (37.3%)

0.003

No AKI-sCr

AKI-sCr

108 (14.0%)

226 (43.8%)

 < 0.001

133 (17.3%)

234 (45.5%)

 < 0.001

95 (27.0%)

195 (42.9%)

 < 0.001

No AKI-UO

AKI-UO

33 (13.9%)

300 (28.7%)

 < 0.001

40 (16.9%)

326 (31.3%)

 < 0.001

28 (27.5%)

261 (37.2%)

0.056

RR-AKI

P-AKI

23 (18.4%)

311 (26.8%)

0.042

29 (23.2%)

338 (29.2%)

0.158

22 (36.1%)

268 (35.9%)

0.982

No AKD

AKD

9 (5.7%)

325 (28.8%)

 < 0.001

11 (6.9%)

356 (31.7%)

 < 0.001

8 (17.8%)

282 (37.0%)

0.009

No KRT

KRT

263 (22.7%)

71 (56.3%)

 < 0.001

295 (25.5%)

72 (57.1%)

 < 0.001

232 (33.9%)

58 (47.5%)

0.004

Length of stay (days)

All

No AKI

AKI

11 (5.3, 22)

5 (2.8, 7.9)

12.1 (6.7, 24)

 < 0.001

18 (7, 34)

13.5 (6, 22)

19 (7, 36)

 < 0.001

/

/

(b) Kidney outcomes

AKI

1095/1286 (85.1%)

ICU day start AKI (d)

2 (1, 2)

ICU day AKI max (d)

2 (2, 4)

Duration of AKI (d)

5 (3, 9)

RR-AKI

125 (11.4%)

AKD (n = 1286)

AKD–no AKI (n = 191)

AKD–AKI (n = 1095)

1127 (87.6%)

32 (2.8% of all AKD)

1095 (97.2% of all AKD)

KRT (n = 1286)

CKRT

IHD

126 (9.8%)

75 (59.5%)

51 (40.5%)

KRT start (d of ICU/date)

7 (2, 12)

KRT end (d of ICU/date)

17 (10, 22)

Duration KRT (d) (n = 96)

8 (3, 14)

Kidney recovery (ICU survivors)

AKI (n = 773)

AKI-sCr (n = 290)

AKI-UO (n = 740)

AKI-UO excl KRT (n = 725)

AKI-sCr vs AKI-UO: p < 0.001

369 (47.7%)

199 (68.6%)

407 (55.0%)

397 (54.8%)

sCr@d21/ICU discharge (mg/dl)

All ICU survivors (n = 952)

No AKI (n = 179)

AKI (n = 773)

no AKI versus AKI p = 0.266

0.73 (0.61, 0.93)

0.70 (0.65, 0.90)

0.72 (0.60, 0.95)

KRT at 21 days or ICU discharge (n = 95)

64 (67.4%)