From: Extended prone positioning duration for COVID-19-related ARDS: benefits and detriments
Variables | Patients without pressure injury (n = 60) n/N (%) or med (Q1–Q3) | Patients with at least one pressure injury (n = 21) n/N (%) or med (Q1–Q3) | OR (95% CI) | p |
---|---|---|---|---|
Sex, male | 40/60 (67) | 18/21 (86) | 3.00 (0.88–13.88) | 0.081 |
Age, years | 60 (51–68) | 58 (52–63) | 1.00 (0.96–1.05) | 0.91 |
BMI, kg/m2 | 30 (27–37) | 33 (29–36) | 0.99 (0.94–1.01) | 0.54 |
Type 2 diabetes | 13/60 (22) | 7/21 (33) | 1.43 (0.50–3.88) | 0.49 |
History of cardiovascular disease* | 7/60 (12) | 1/21 (5) | 0.38 (0.02–2.32) | 0.33 |
History of respiratory disease** | 6/60 (10) | 2/21 (10) | 0.95 (0.13–4.53) | 0.95 |
SAPS II score | 36 (30–48) | 39 (33–42) | 0.99 (0.95–1.02) | 0.43 |
PaO2/FiO2 ratio before first pronation session, mmHg | 82 (68–114) | 88 (75–99) | 1.00 (0.98–1.01) | 0.65 |
ECMO | 12/60 (20) | 5/21 (24) | 1.25 (0.35–3.96) | 0.71 |
Nitric oxide | 25/60 (42) | 9/21 (43) | 1.05 (0.38–2.86) | 0.92 |
At least one proning session with catecholamines | 28/60 (47) | 9/21 (43) | 0.86 (0.31–2.33) | 0.76 |
Duration of mechanical ventilation, days | 14 (9–25) | 29 (22–34) | 1.01 (1.00–1.02) | 0.12 |
ICU length of stay, days | 17 (11–26) | 29 (19–34) | 1.05 (1.01–1.10) | 0.021 |
Median duration of each proning sessions, h | 40 (35–43) | 36 (32–40) | 0.96 (0.89–1.03) | 0.26 |
Cumulated duration of all proning sessions, days*** | 3 (2–5) | 6 (4–8) | 1.33 (1.11–1.63) | 0.0015 |