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Table 4 Factors associated with the occurrence of pressure injuries (univariate logistic regression)

From: Extended prone positioning duration for COVID-19-related ARDS: benefits and detriments

Variables

Patients without pressure injury (n = 60)

n/N (%) or med (Q1–Q3)

Patients with at least one pressure injury (n = 21)

n/N (%) or med (Q1–Q3)

OR (95% CI)

p

Sex, male

40/60 (67)

18/21 (86)

3.00 (0.88–13.88)

0.081

Age, years

60 (51–68)

58 (52–63)

1.00 (0.96–1.05)

0.91

BMI, kg/m2

30 (27–37)

33 (29–36)

0.99 (0.94–1.01)

0.54

Type 2 diabetes

13/60 (22)

7/21 (33)

1.43 (0.50–3.88)

0.49

History of cardiovascular disease*

7/60 (12)

1/21 (5)

0.38 (0.02–2.32)

0.33

History of respiratory disease**

6/60 (10)

2/21 (10)

0.95 (0.13–4.53)

0.95

SAPS II score

36 (30–48)

39 (33–42)

0.99 (0.95–1.02)

0.43

PaO2/FiO2 ratio before first pronation session, mmHg

82 (68–114)

88 (75–99)

1.00 (0.98–1.01)

0.65

ECMO

12/60 (20)

5/21 (24)

1.25 (0.35–3.96)

0.71

Nitric oxide

25/60 (42)

9/21 (43)

1.05 (0.38–2.86)

0.92

At least one proning session with catecholamines

28/60 (47)

9/21 (43)

0.86 (0.31–2.33)

0.76

Duration of mechanical ventilation, days

14 (9–25)

29 (22–34)

1.01 (1.00–1.02)

0.12

ICU length of stay, days

17 (11–26)

29 (19–34)

1.05 (1.01–1.10)

0.021

Median duration of each proning sessions, h

40 (35–43)

36 (32–40)

0.96 (0.89–1.03)

0.26

Cumulated duration of all proning sessions, days***

3 (2–5)

6 (4–8)

1.33 (1.11–1.63)

0.0015

  1. BMI, Body Mass Index; SAPS II, simplified acute physiology score; ECMO, Extracorporeal Membrane Oxygenation; PaO2, partial pressure of dioxide in arterial blood; FiO2, fraction of inspired oxygen; ICU, intensive care unit; PP, prone positioning
  2. ***This duration is the added duration of all PP sessions for each patient *chronic heart failure, ischemic heart disease or peripheral arterial disease; **chronic obstructive pulmonary disease or Asthma
  3. Bold formatting of p value indicates a statistically significant value