Table 2 ICU admission and ICU course of disease according to disease categories
| Â | CV disorder | Neuromuscular disorder | Encephalopathy | Infl. CNS disorder | Epileptic disorder | Other | Total |
|---|---|---|---|---|---|---|---|
N | 161 | 80 | 181 | 7 | 40 | 61 | 392 |
Reason for admission (N = 387) |  |  |  |  |  |  |  |
 Respiratory failure | 106 (66.7%) | 71 (91.0%) | 153 (85.5%) | 5 (71.4%) | 34 (87.2%) | 38 (88.4%) | 312 (80.6%) |
 Circulatory failure | 18 (11.3%) | 11 (14.1%) | 23 (12.8%) | 1 (14.3%) | 2 (5.1%) | 6 (14.0%) | 40 (10.3%) |
 Impaired consciousness | 14 (8.8%) | 1 (1.3%) | 19 (10.6%) | 1 (14.3%) | 4 (10.3%) | 3 (7.0%) | 33 (8.5%) |
 Other reasons | 48 (30.2%) | 9 (11.5%) | 19 (10.6%) | 2 (28.6%) | 7 (17.9%) | 3 (7.0%) | 69 (17.8%) |
ICU course of disease | Â | Â | Â | Â | Â | Â | Â |
 Vasopressors (N = 388) | 126 (78.8%) | 72 (90.0%) | 146 (82.0%) | 6 (85.7%) | 30 (76.9%) | 41 (97.6%) | 315 (81.2%) |
 Invasive ventilation (N = 389) | 131 (81.9%) | 75 (93.8%) | 142 (79.3%) | 6 (85.7%) | 30 (75.0%) | 41 (97.6%) | 319 (82.0%) |
 ARDS (N = 388) | 98 (61.3%) | 69 (87.3%) | 135 (75.8%) | 6 (85.7%) | 26 (65.0%) | 36 (85.7%) | 277 (71.4%) |
 Use of ECMO (N = 385) | 47 (29.6%) | 28 (35.4%) | 31 (17.6%) | 2 (28.6%) | 9 (22.5%) | 20 (47.6%) | 91 (23.6%) |
 Sepsis (N = 385) | 81 (50.6%) | 52 (65.8%) | 103 (58.5%) | 3 (42.9%) | 24 (61.5%) | 28 (66.7%) | 212 (55.1%) |
 Acute kidney failure (N = 386) | 67 (41.9%) | 39 (49.4%) | 88 (49.7%) | 5 (71.4%) | 20 (51.3%) | 26 (61.9%) | 172 (44.6%) |
 Acute liver failurea (N = 378) | 27 (17.3%) | 8 (10.5%) | 22 (12.6%) | 0 (0.0%) | 4 (10.5%) | 6 (14.3%) | 48 (12.7%) |
Scores (mean ± SD) |  |  |  |  |  |  |  |
 GCS (Min.) (N = 350) | 7.5 ± 4.6 | 11.3 ± 4.3 | 10.1 ± 4.2 | 10.0 ± 4.2 | 8.1 ± 4.8 | 7.7 ± 5.2 | 9.8 ± 4.7 |
 RASS (Min.) (N = 343) | − 2.6 ± 2.2 | − 1.0 ± 1.7 | − 1.3 ± 2.3 | − 0.8 ± 1.3 | − 2.6 ± 2.3 | − 2.7 ± 2.3 | − 1.6 ± 2.3 |
 RASS (Max.) (N = 343) | − 2.3 ± 2.3 | − 0.7 ± 1.5 | − 0.9 ± 2.2 | − 0.6 ± 1.1 | − 2.0 ± 2.3 | − 2.6 ± 2.3 | − 1.3 ± 2.2 |
 FOUR (Min.) (N = 254) | 8.3 ± 5.8 | 12.2 ± 3.7 | 11.3 ± 4.7 | 11.2 ± 3.8 | 8.9 ± 5.7 | 7.1 ± 6.7 | 10.8 ± 5.3 |
 SAPS (Max.) (N = 155) | 49.5 ± 20.5 | 38.4 ± 17.4 | 45.1 ± 16.8 | 39.0 ± 18.4 | 41.6 ± 17.3 | 46.2 ± 18.4 | 43.6 ± 18.0 |
 SOFA respiratory system (Max.) (N = 187) | 2.5 ± 1.2 | 2.2 ± 0.9 | 2.4 ± 1.0 | 1.8 ± 1.0 | 2.6 ± 1.3 | 2.8 ± 1.2 | 2.4 ± 1.1 |
 SOFA circulatory system (Max.) (N = 178) | 2.3 ± 1.4 | 1.7 ± 1.1 | 2.1 ± 1.2 | 1.0 ± 0.0 | 2.6 ± 1.4 | 2.5 ± 1.3 | 2.2 ± 1.3 |
 Time from onset of COVID symptoms to first neurologic symptoms (Days; Median (IQR)) (N = 322) | 10 (1, 23) | 26 (20, 38) | 12 (3, 25) | 30 (25, 41) | 8 (4, 25) | 13.5 (0.5, 26) | 13 (3, 25) |