Skip to main content

Table 1 Baseline characteristics according to disease categories in 392 patients

From: Neurologic manifestations of COVID-19 in critically ill patients: results of the prospective multicenter registry PANDEMIC

Disease categoriesb

       
 

CV disorders

Neuromuscular disorder

Encephalopathy

Inflamatory CNS disorders

Epileptic disorders

Other

Total

Na

161

80

181

7

40

61

392

Demographics

       

 Age (mean ± SD)

67.0 ± 13.4

61.6 ± 12.8

66.6 ± 12.7

61.9 ± 9.3

62.5 ± 13.3

60.3 ± 9.7

65.3 ± 13.1

 Sex

       

  Male

112 (69.6%)

59 (73.8%)

131 (72.4%)

6 (85.7%)

27 (67.5%)

43 (70.5%)

277 (70.7%)

  Female

49 (30.4%)

21 (26.3%)

50 (27.6%)

1 (14.3%)

13 (32.5%)

18 (29.5%)

115 (29.3%)

 Nicotine consumption (N = 184)

20 (25.3%)

12 (28.6%)

22 (31.0%)

0 (0.0%)

8 (36.4%)

10 (28.6%)

50 (27.2%)

 Alcohol consumptionc (N = 260)

8 (7.3%)

2 (3.8%)

10 (8.5%)

0 (0.0%)

5 (14.7%)

1 (2.2%)

17 (6.5%)

Past medical history

       

 Neurological diseased (N = 386)

47 (29.7%)

14 (17.5%)

43 (24.3%)

2 (28.6%)

11 (28.2%)

11 (18.3%)

88 (22.8%)

 Cardiovascular disease (N = 375)

105 (68.2%)

48 (61.5%)

124 (72.5%)

3 (42.9%)

25 (65.8%)

36 (63.2%)

262 (69.9%)

 Coronary heart disease (N = 383)

30 (19.5%)

6 (7.9%)

28 (16.5%)

0 (0.0%)

2 (5.4%)

6 (10.5%)

54 (14.5%)

 Lung disease (N = 368)

28 (18.5%)

8 (10.8%)

38 (22.5%)

2 (28.6%)

7 (18.4%)

8 (14.0%)

69 (18.8%)

 Diabetes (N = 373)

47 (30.5%)

20 (26.3%)

46 (27.1%)

0 (0.0%)

12 (32.4%)

19 (33.3%)

110 (29.5%)

 Dyslipidemia (N = 373)

30 (19.5%)

11 (14.5%)

29 (17.1%)

0 (0.0%)

7 (18.9%)

9 (15.8%)

63 (16.9%)

 Hypertension (N = 373)

87 (56.5%)

38 (50.0%)

104 (61.2%)

2 (33.3%)

20 (54.1%)

30 (52.6%)

224 (60.1%)

Pre-hospital medications

       

 Anticoagulant drugs (N = 322)

50 (36.2%)

15 (22.7%)

53 (35.8%)

1 (14.3%)

12 (38.7%)

14 (26.9%)

107 (33.2%)

 Immunosuppressants (N = 376)

18 (11.8%)

8 (10.1%)

21 (12.2%)

1 (14.3%)

9 (23.1%)

9 (15.3%)

45 (12.0%)

pmRS (N = 322)

       

 0

90 (65.2%)

38 (57.6%)

79 (52.3%)

3 (42.9%)

17 (50.0%)

42 (84.0%)

197 (61.2%)

 1

16 (11.6%)

13 (19.7%)

32 (21.2%)

2 (28.6%)

8 (23.5%)

5 (10.0%)

49 (15.2%)

 2

8 (5.8%)

6 (9.1%)

15 (9.9%)

1 (14.3%)

3 (8.8%)

1 (2.0%)

25 (7.8%)

 3

6 (4.3%)

2 (3.0%)

11 (7.3%)

0 (0.0%)

3 (8.8%)

1 (2.0%)

20 (6.2%)

 4

8 (5.8%)

4 (6.1%)

11 (7.3%)

0 (0.0%)

1 (2.9%)

0 (0.0%)

18 (5.6%)

 5

10 (7.2%)

3 (4.5%)

3 (2.0%)

1 (14.3%)

2 (5.9%)

1 (2.0%)

13 (4.0%)

  1. pmRS: premorbid modified Ranking Score (pmRS score; a 7-point scale reflecting daily functioning ranging from 0 (full independence without symptoms) to 6 (death)). SD: Standard Deviation
  2. aNumber of data sets used for analysis is mentioned, where N < 392 (total number of patients included), values are missing
  3. bCerebrovascular disorder (= ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, posterior reversible encephalopathy syndrome, reversible cerebral vasoconstriction syndrome, cerebral venous sinus thrombosis, cerebral microbleeds, subdural hematoma); neuromuscular disorder (NMD)(= critical illness polyneuropathy or myopathy, Guillain–Barré syndrome, myasthenia, myositis); encephalopathy (= delirium, disorder of consciousness, hypoxic encephalopathy, encephalopathy no further described); inflammatory CNS disorder (= meningitis, encephalitis, meningoencephalitis, herpes zoster oticus, polyneuritis cranialis); epileptic disorder (= seizures, status epilepticus); other (= brain edema, exophthalmus, tetraparesis, facial palsy, plexus lesion, phobic gait disorder, major depression, restless legs syndrome, gaze palsy, fine motor impairment)
  4. cMore than two standard drinks a day
  5. dNeurologic disorder included (main categories: ischemic stroke, hemorrhagic stroke, subarachnoid hemorrhage, dementia, epileptic disorder, Parkinson’s disease, traumatic brain injury, myasthenia gravis, multiple sclerosis, others)
Back to article page

Critical Care

ISSN: 1364-8535