| All patients | A | B | C | D | E | F |
---|---|---|---|---|---|---|---|
Age | 52 (33–67) | 53 (36–67) | 56.5 (42–69) | 58 (48–74.5) | 52 (29–67) | 47.5 (32–62) | 44 (29–62) |
Male sex | 1269 (73.4) | 370 (74.4) | 177 (67.6) | 40 (83.3) | 241 (70.3) | 277 (76.9) | 164 (75.2) |
Decompressive Craniectomy | 216 (12.5) | 22 (4.4) | 48 (18.3) | 7 (14.6) | 40 (11.7) | 73 (20.3) | 26 (11.9) |
ISS | 29 (25–41) | 25 (16–34) | 26 (25–38) | 29.5 (25–41.5) | 29 (25–41) | 38 (25–52.5) | 38 (25–50) |
Head ISS | 25 (16–25) | 16 (9–16) | 25 (16–25) | 25 (16–25) | 25 (16–25) | 25 (25–25) | 25 (16–25) |
Highest extracranial ISS | 9 (0–16) | 4 (0–16) | 4 (0–9) | 9 (0–10.75) | 9 (0–16) | 9 (0–16) | 9 (0.25–16) |
Intubation | 1334 (78.9) | 218 (45.7) | 224 (85.8) | 39 (84.8) | 314 (93.2) | 347 (97.5) | 192 (89.7) |
ICP monitoring | 757 (44.2) | 76 (15.6) | 153 (58.4) | 19 (40.4) | 177 (51.8) | 225 (62.7) | 107 (49.5) |
Median daily TIL | 2 (0–5.5) | 0.5 (0–1.5) | 3.5 (0.5–8) | 2 (0–3.25) | 3 (1–5) | 4.5 (2–8.5) | 3 (1–5.625) |
GOS-E at 6Â months | |||||||
1 | 388 (22.5) | 34 (6.8) | 77 (29.4) | 19 (39.6) | 62 (18.1) | 135 (37.5) | 61 (28) |
2 or 3 | 268 (15.5) | 40 (8) | 50 (19.1) | 5 (10.4) | 70 (20.4) | 68 (18.9) | 35 (16.1) |
4 | 123 (7.1) | 31 (6.2) | 19 (7.3) | 6 (12.5) | 27 (7.9) | 21 (5.8) | 19 (8.7) |
5 | 241 (13.9) | 71 (14.3) | 34 (13) | 5 (10.4) | 49 (14.3) | 47 (13.1) | 35 (16.1) |
6 | 214 (12.4) | 70 (14.1) | 31 (11.8) | 5 (10.4) | 51 (14.9) | 29 (8.1) | 28 (12.8) |
7 | 229 (13.3) | 107 (21.5) | 24 (9.2) | 2 (4.2) | 40 (11.7) | 37 (10.3) | 19 (8.7) |
8 | 265 (15.3) | 144 (29) | 27 (10.3) | 6 (12.5) | 44 (12.8) | 23 (6.4) | 21 (9.6) |
Mortality, % | 22 | 7 | 29 | 40 | 18 | 38 | 28 |
Unfavourable outcome, % | 45 | 21 | 56 | 63 | 46 | 62 | 53 |
IMPACT predicted mortality, mean (SD) | 27 | 13 (8) | 27 (18) | 30 (23) | 24 (16) | 45 (18) | 32 (22) |
IMPACT predicted unfavourable outcome, mean (SD) | 45 | 26 (15) | 46 (24) | 48 (27) | 43 (22) | 70 (18) | 51 (26) |
Difference between predicted and observed mortality, % | 5 | 6 | − 2 | − 10 | 6 | 7 | 4 |
Difference between predicted and observed unfavourable outcome, % | 0 | 5 | − 10 | − 15 | − 3 | 8 | − 2 |