Training cohort (n = 3899)1 | Testing cohort (n = 6848)1 | |||
---|---|---|---|---|
Colonization | No colonization | Colonization | No colonization | |
Total, n1 (%) | 575 (15) | 3324 (85) | 588 (9) | 6260 (91) |
Patients4 | ||||
Male, n (%) | 372 (65) | 2,167 (65) | 359 (61) | 4023 (64) |
Age, median [IQR] | 67 [55–77] | 64 [52–75] | 64 [55–74] | 64.0 [54–74] |
BMI2, median [IQR] | 27 [23–31] | 26 [22–29] | 28 [23–33] | 26 [23–31] |
Obesity5, n (%) | 165 (29) | 680 (21) | 207 (35) | 1663 (27) |
Diabetes, n (%) | 162 (28) | 671 (20) | 58 (10) | 570 (9) |
SAPS23, median [IQR] | 57 [45–70] | 55 [42–70] | 57 [43–73] | 57 [44–73] |
Mechanical ventilation, n (%) | 442 (77) | 2685 (81) | 439 (75) | 4584 (73) |
Antibiotic therapy at admission, n (%) | 331 (58) | 1969 (59) | 357 (61) | 4056 (65) |
Vasopressors at admission, n (%) | 327 (57) | 1962 (59) | 285 (49) | 3471 (56) |
Catheters | ||||
At insertion | ||||
Type of catheter, n (%) | ||||
Central venous catheter | 371 (65) | 2724 (82) | 320 (54) | 3799 (61) |
Dialysis catheter | 204 (36) | 600 (18) | 268 (46) | 2461 (39) |
First catheter inserted, n (%) | 459 (80) | 2894 (87) | 246 (42) | 2959 (47) |
Skin disinfection with chlorhexidine, n (%) | 132 (23)* | 1280 (39)* | 207 (35) | 3862 (62) |
Skin disinfection with alcohol-based povidone-iodine, n (%) | 419 (73)* | 1851 (56)* | 381 (65) | 2398 (38) |
Insertion site, n (%) | ||||
Subclavian | 34 (6) | 792 (24) | 85 (14) | 1356 (22) |
Jugular | 240 (42) | 1271 (38) | 246 (42) | 2074 (33) |
Femoral | 301 (52) | 1261 (38) | 257 (44) | 2830 (45) |
At removal | ||||
Time to removal > 5 days, n (%) | 354 (62) | 1528 (46) | 380 (65) | 2956 (47) |
Removal for suspected catheter-related infection, n (%) | 120 (21) | 477 (14) | 149 (25) | 723 (12) |