Table 2 Test characteristics of 22-variable TreeNet® PERSEVEREnce model to estimate risk of death or day 7 MODS in children with septic shock
Training set | Test set | |
|---|---|---|
AUROC | 0.93 (0.91–0.95) | 0.80 (0.76–0.84) |
Weighted misclassification rate | 0.16 | 0.26 |
True positive, n | 150 | 125 |
False negative, n | 23 | 48 |
False positive, n | 58 | 83 |
True negative, n | 271 | 246 |
Sensitivity % | 86.7 (80.5, 91.2) | 72.2 (64.8, 78.6) |
Specificity % | 82.3 (77.7, 86.2) | 74.8 (69.7, 79.3) |
Positive predictive value % | 72.1 (65.4, 77.9) | 60.1 (53.1, 66.7) |
Negative predictive value % | 92.1 (88.3, 94.9) | 83.7 (78.8, 87.6) |
Positive likelihood ratio | 4.9 (3.9, 6.3) | 2.9 (2.3, 3.5) |
Negative likelihood ratio | 0.2 (0.1, 0.3) | 0.4 (0.3, 0.5) |