Variable | No death or day 7 MODS | Death or day 7 MODS | P value |
---|---|---|---|
n (%) | 329 (65.5%) | 173 (34.5%) | |
Age* | 4.2 (1.5, 8.2) | 2.7 (0.9, 6.6) | 0.007 |
Sex, M, n (%) | 170 (51.6%) | 92 (53.2%) | 0.748 |
PRISM III** | 10 (6, 15) | 15 (9) | < 0.001 |
Day 1 VIS | 10 (2, 21) | 20 (5, 50) | < 0.001 |
Lactate | 1.2 (0, 2.3) | 1.9 (0.9, 5.1) | < 0.001 |
Positive blood culture | 62 (18.8%) | 44 (25.4%) | 0.086 |
Positive culture (any) | 174 (52.8%) | 108 (62.4%) | 0.016 |
Source of infection: | 0.030 | ||
Pulmonary | 64 (19.4%) | 45 (26.0%) | |
Extrapulmonary | 110 (33.4%) | 63 (36.4%) | |
Organism | 0.052 | ||
Gram positive | 78 (23.7%) | 44 (25.4%) | |
Gram negative | 60 (18.2%) | 41 (23.6%) | |
Viral | 22 (6.6%) | 13 (7.5%) | |
Fungal | 8 (2.4%) | 3 (1.7%) | |
Organ dysfunctions on day 7 | |||
Max. number of organ failures | 0 (0, 1) | 2 (1, 3) | < 0.001 |
Cardiovascular | 9 | 113 | < 0.001 |
Respiratory | 38 | 155 | < 0.001 |
Renal | 14 | 129 | < 0.001 |
Hepatic | 6 | 77 | < 0.001 |
Hematologic | 11 | 96 | < 0.001 |
Neurologic | 0 | 41 | < 0.001 |
Organ support on day 7 | |||
Vasoactive support | 11 (3.3%) | 103 (59.5%) | < 0.001 |
Mechanical ventilation | 46 (13.9%) | 158 (91.3%) | < 0.001 |
Renal replacement therapy | 5 (1.5%) | 66 (38.5%) | < 0.001 |
Steroids | 158 (48.1%) | 101 (58.3%) | 0.027 |
28-day Mortality | 2 (0.6%) | 61 (35.3%) | < 0.001 |
PICU LOS days | 5 (7) | 12 (13) | < 0.001 |
PICU-free days | 23 (7) | 15 (16) | < 0.001 |