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Table 1 Patient characteristics

From: Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia

 

Culture negative (N = 53)

Culture positive (N = 37)

p

Age, median (IQR) yrs

59.0 (48–68)

56.5 (38.0–66.5)

0.275

Male, n (%)

35 (66.0)

23 (62.2)

0.877

Days on MV*, median (IQR)

8 (4.5–12.5)

7 (5–10)

0.697

Admission type, n (%)

  

0.218

 Medical

29 (54.7)

13 (35.1)

 

 Planned surgical

10 (18.9)

11 (29.7)

 

 Emergency surgical

13 (24.5)

13 (35.1)

 

 Unrecorded

1 (1.9)

0

 

Trauma, n (%)

12 (22.6)

18 (48.6)

0.019

Neurosurgery, n (%)

11 (20.8)

12 (32.4)

0.315

COPD, n (%)

8 (15.1)

5 (13.5)

1.000

ARDS, n (%)

3 (5.7)

0 (0.0)

0.381

APACHEII score, median (IQR)

21 (15–24)

14 (10–20)

0.009

CPIS score, median (IQR)

5 (4–6)

7 (6–7)

 < 0.001

Tmax, °C, median (IQR)

38 (37–39)

38 (37–38)

0.551

WCC, median (IQR) 109/ml

15.5 (11.3–21.0)

13 (11–17)

0.074

PaO2/FiO2 max, median (IQR) mmHg

240 (180–283.5)

232.5 (168.8–283.1)

0.85

Pmax, median (IQR) cmH2O

20 (16–25)

21 (16–24)

0.874

PEEP, median (IQR) cmH2O

8 (5–10)

8 (5–10)

0.983

Tidal volume, median (IQR) ml

479 (429.5–580)

538 (449–620)

0.298

Genus culture results**, n (%)

   

 Enterobacter

 

2 (5.4)

 

 Escherichia

 

2 (5.4)

 

 Haemophilus

 

4 (10.8)

 

 Klebsiella

 

4 (10.8)

 

 Pseudomonas

 

10 (27.0)

 

 Serratia

 

1 (2.7)

 

 Staphylococcus

 

13 (35.1)

 

 Stenotrophomonas

 

1 (2.7)

 

ICU LOS, median (IQR) days

18 (14.0–26.8)

22 (16–35)

0.154

Hospital LOS, median (IQR) days

26.5 (15.5–42.8)

34 (21.8–64.5)

0.284

ICU mortality, n (%)

12 (22.6)

4 (10.8)

0.244

  1. ARDS acute respiratory distress syndrome, APACHE acute physiology and chronic health evaluation, CPIS clinical pulmonary infection score, Tmax maximum temperature, WCC white cell count, FiO2 max maximum inspired fraction of oxygen ratio, Pmax maximum airway pressure, PEEP positive end-expiratory pressure, LOS length of stay
  2. *Days on mechanical ventilation (MV) until VAP suspicion
  3. **Potentially > 1 cultured pathogen per patient