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Fig. 2 | Critical Care

Fig. 2

From: Dynamics of disease characteristics and clinical management of critically ill COVID-19 patients over the time course of the pandemic: an analysis of the prospective, international, multicentre RISC-19-ICU registry

Fig. 2

Dynamics of vitals and laboratory parameters at intensive care unit admission. Mean effects over the time course of the pandemic, calculated by means of generalized mixed-effect models, are depicted by a red continuous line. 95% confidence intervals of the effect are depicted as shaded red area. The given p values originate from an analysis of deviance. Variables are represented by topographic density plots, in which the intensity of the grayscale colouring indicates the highest concentration of values

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