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Table 4 Comparison between 2011–2021 and 2000–2010 decades regarding the modality of fluid challenge administration

From: Fluid challenge in critically ill patients receiving haemodynamic monitoring: a systematic review and comparison of two decades

General characteristics

2011–2021

2000–2010

p value

Fluid responders (%)

52 (45–60)

52 (43–62)

0.32

Crystalloids versus colloids (n. of studies)

57 versus 32

11 versus 20

0.007

Volume (ml)

500 (500–500)

500 (500–500)

0.32

Time of infusion (min)

15 (10–30)

30 (15–30)

0.03

Threshold 10% versus 15% (n. of studies)

30 versus 62

6 versus 26

0.17

CO/CI versus SV/SVI (n. of studies)

61 versus 30

18 versus 12

0.51

  1. CO, cardiac output; CI, cardiac index; SV, stroke volume; SVI, stroke volume index