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Table 4 Unadjusted analysis of clinical outcomes according to early sedation depth

From: A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study

Outcome

Light sedation (n = 108)

Deep sedation (n = 283)

OR or between-group difference

(95% CI)

p

Ventilator-free days

20.7 (9.6)

14.7 (11.4)

6.04 (3.60–8.48)

 < 0.01

ICU-free days

18.3 (9.9)

12.1 (11.0)

6.20 (3.82–8.57)

 < 0.01

Hospital-free days

13.8 (10.3)

8.0 (9.6)

5.74 (3.56–7.92)

 < 0.01

Mortality, n (%)

12 (11.1)

86 (30.4)

3.49 (1.82–6.70)

 < 0.01

  1. ICU, intensive care unit; OR, odds ratio; CI, confidence interval