Predictors | Early mortality | Late mortality | ||
---|---|---|---|---|
Hazard ratio* | p value | Hazard ratio* | p value | |
Non-focal ARDS | 4.40 [1.93–10.01] |  < 0.001 | 2.79 [0.81–9.63] | 0.106 |
Age | 1.04 [1.02–1.07] |  < 0.001 | 1.03 [0.99–1.07] | 0.126 |
Males | 0.85 [0.45–1.60] | 0.618 | 0.82 [0.25–2.74] | 0.751 |
Haematological cancers | 2.27 [0.95–5.43] | 0.064 | 1.73 [0.17–17.70] | 0.642 |
Non-haematological cancers | 2.09 [0.95–4.57] | 0.066 | 1.48 [0.39–5.68] | 0.566 |
COPD | 1.33 [0.55–3.25] | 0.525 | 2.30 [0.54–9.84] | 0.263 |
McCabe | 1.11 [0.71–1.73] | 0.645 | 3.56 [1.45–8.72] | 0.005 |
BMI | 0.99 [0.94–1.05] | 0.789 | 0.93 [0.84–1.04] | 0.213 |
SAPS II (without age)†| 1.02 [1.00–1.04] | 0.047 | 1.02 [0.98–1.07] | 0.357 |
PaO2/FiO2 | 1.00 [1.00–1.01] | 0.586 | 0.99 [0.98–1.00] | 0.065 |
Plateau pressure | 1.12 [0.91–1.37] | 0.285 | 0.86 [0.59–1.25] | 0.426 |
PEEP | 0.90 [0.74–1.10] | 0.305 | 1.07 [0.72–1.58] | 0.740 |
Driving pressure | 0.91 [0.74–1.11] | 0.360 | 1.16 [0.80–1.68] | 0.426 |
Shock | 1.24 [0.67–2.27] | 0.493 | 1.55 [0.48–5.06] | 0.466 |
Mechanical ventilation over 48 h | 2.08 [0.61–7.09] | 0.243 | 0.71 [0.15–3.28] | 0.659 |
Steroid | 1.13 [0.63–2.03] | 0.689 | 1.66 [0.54–5.12] | 0.381 |
Renal replacement therapy | 2.42 [1.40–4.20] | 0.002 | 0.29 [0.06–1.46] | 0.133 |
Intervention arm in LIVE study$ | 0.65 [0.38–1.11] | 0.115 | 1.66 [0.56–4.96] | 0.362 |