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Table 2 Association between septic shock case volume quartile and hospital mortality of septic shock

From: Association of annual hospital septic shock case volume and hospital mortality

Sample

Unadjusted

Model 1

Model 2

Model 3

Model 4

Interaction p valuesa

First quartile

Ref

Ref

Ref

Ref

Ref

Second quartile

− 0.35 (− 0.47, − 0.22)

− 0.30 (− 0.44, − 0.16)

− 0.29 (− 0.43, − 0.14)

− 0.28 (− 0.43, − 0.13)

− 0.29 (− 0.43, − 0.14)

< 0.001b

Third quartile

− 0.69 (− 0.81, − 0.56)

− 0.63 (− 0.78, − 0.49)

− 0.62 (− 0.77, − 0.47)

− 0.62 (− 0.77, − 0.47)

− 0.62 (− 0.77, − 0.47)

< 0.001c

Fourth Quartile

− 0.86 (− 0.98, − 0.74)

− 0.80 (− 0.95, − 0.66)

− 0.79 (− 0.95, − 0.64)

− 0.79 (− 0.94, − 0.64)

− 0.79 (− 0.94, − 0.64)

0.037d

  1. Model 1, model adjusted for type of hospitals, geographic location, site of infection (sites of bloodstream, urinary, skin, central nervous system, lung, bone, abdominal, gastrointestinal), the proportion of APACHE II score ≥ 15, and proportion of age ≥ 60
  2. Model 2, adjusted for model 1 + microbiology specimen collection before antibiotic therapy
  3. Model 3, adjusted for model 2 + infection management, infection training, infection monitor, infection contingency plan, infection performance
  4. Model 4, adjusted for model 3 + adherence to 3-h bundle
  5. aInteraction p values comparisons of Model 4 between case volume quartiles were made using the Turkey's test
  6. bComparison between second quartile and first quartile
  7. cComparison between third quartile and second quartile
  8. dComparison between fourth quartile and third quartile