Table 1 Baseline characteristics of included patients (stratified by survival status to day 28)
Survivor (N = 387, 75.7%) | Non-survivor (N = 124, 24.3%) | p-value | |
|---|---|---|---|
Log baseline IL-18 | 6.71 (0.91) | 7.06 (1.0) | < 0.001 |
Age (years) | 51.51 (15.9) | 59.40 (16.8) | < 0.001 |
Baseline APACHE II scorea | 17.95 (6.5) | 21.87 (6.3) | < 0.001 |
Body mass index | 27.4 (6.9) | 26.7 (6.5) | 0.31 |
Pre-randomisation P/F ratio (kPa) | 17.41 (7.27) | 16.14 (7.14) | 0.05 |
Sepsis—N (%) | 287 (74.2) | 99 (79.8) | 0.20 |
Vasopressor use—N (%) | 237 (61.2) | 95 (76.6) | 0.002 |