Fig. 3From: Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndromeDuration–effect and dose–effect relationship between ketamine (propofol) and total bilirubin levels. Time-varying, weighted cumulative exposure mixed-effects model assessing the multivariable adjusted duration of infusion–effect (a) and dose–effect (b) relationship of ketamine (propofol (c, d)) on rising bilirubin levels. Model estimates are depicted as solid lines and 95% confidence intervals as shaded areasBack to article page