Sorbent material |
High selectivity/affinity to enable sharp separation |
High capacity to minimize the amount of sorbent needed |
Favorable kinetic and transport properties for rapid sorption |
Chemical and thermal stability; low solubility when contacting fluid |
Hardness and mechanical strength to prevent crushing and erosion |
Free flowing tendency for easy filling and emptying of the packed beads |
High resistance to fouling for long life and low solute interference |
No tendency to promote undesirable chemical reactions or side effects |
Relatively low cost |
Sorbent cartridge |
Adequate design in terms of length and diameter |
Adequate internal volume to avoid excessive blood priming volume |
Avoidance of dead space zones where easy clotting may occur |
Adequate packing density of the sorbent particles |
Low resistance to blood flow of the packed bed |
Adequate retention screens at the ports to avoid sorbent particles dissemination |
Mass transfer zone shorter than unit length |