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Fig. 3 | Critical Care

Fig. 3

From: Clinical and biochemical endpoints and predictors of response to plasma exchange in septic shock: results from a randomized controlled trial

Fig. 3

Modulation of TPE effect on norepinephrine dose and lactate concentrations. Shown are both observed A, C and estimated B, D norepinephrine doses (NE) as well as lactate concentrations for the standard of care (SOC) and therapeutic plasma exchange (TPE) group during the first 24 h since randomization. Estimated values were calculated using a linear mixed-effects model. The models indicated a continuous effect of TPE on the reduction in NE doses (p = 0.004) and lactate concentrations (p = 0.001) over the initial 24 h

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