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Table 1 Characteristics of COVID-19 patients and SARS-CoV-2– patients hospitalized for severe community-acquired pneumonia (CAP) participating in the study

From: Impairment of neutrophil functions and homeostasis in COVID-19 patients: association with disease severity

Characteristics

COVID-19

CAP

P value

N = 90

N = 

Men (N, %)

57 (63%)

14 (64%)

NS

Age (years, SD)

63 ± 11

69 ± 17

0.0171

SOFA score Day 1

3.5 [0–12]

6 [1–13]

0.0065

Body mass index

 < 30

47 (52%)

16 (73%)

NS

 > 30

40 (44%)

5 (25%)

NS

Comorbidity (N, %)

Arterial hypertension

60 (67%)

10 (45%)

NS

Diabetes mellitus

35 (39%)

6 (27%)

NS

Chronic renal failure

5 (6%)

2 (9%)

NS

Cirrhosis

1 (1%)

2 (9%)

NS

Previous cancer:

2 (2%)

2 9%)

NS

Hematological malignancy:

1 (1%)

0 (0%)

NS

Immune deficiency

11 (12%)

2 (9%)

NS

Treatment (N, %)

Corticosteroids

90 (100%)

2 (9%)

NS

Tocilizumab

9 (10%)

0 (0%)

NS

Organ support therapy (N, %)

Mechanical ventilation

50 (56%)

8 (28%)

NS

Hemodialysis

9 (10%)

2 (9%)

NS

Biological data (mean) [min–max]

Neutrophil count (G/L)

7.59 [0.78–22.8]

11.55 [2.7–19.4]

0.0047

Lymphocyte count (G/L)

0.76 [0.12–1.87]

0.84 [0.16–1.51]

NS

CRP (mg/L)

152 [0–428]

253 [0–418]

0.0094

Fibrinogen (g/L)

6.9 [4.84–9]

6.61 [1.29–10.2]

NS

  1. Sex, risk factors, and type of treatment were compared with the χ2 test. The Mann–Whitney test was used to compare quantitative variables
  2. Biological data have been measured at the admission of patients to ICU (Day 1)
  3. SOFA Sequential Organ Failure Assessment, CRP C-reactive protein, NS not significant